Protein Alignment SIFaR and prlhr

DIOPT Version :10

• Sequence 1: NP_650966.2
• Gene: SIFaR / 42530
• FlyBaseID: FBgn0038880
• Length: 758
• Species: Drosophila melanogaster
• Sequence 2: XP_002940396.1
• Gene: prlhr / 100497660
• XenbaseID: XB-GENE-994391
• Length: 343
• Species: Xenopus tropicalis
• Alignment Length: 346
• Identity: 101/346 - (29%)
• Similarity: 164/346 - (47%)
• Gaps: 50/346 - (14%)

  Fly   161 NLSPATTSLISAAAATKSYNDSALRWEQLDGSVDFGFDPLYRHSLAMSMVYCVAYIVVFLVGLIG 225
            |:| .|.||..|.|:..|.....|:               ..||....::.|  |.:|...|:.|
 Frog     5 NIS-TTQSLFPAMASNSSQQFMGLQ---------------LIHSYKALIIPC--YSLVVFTGIFG 51

  Fly   226 NSFVIAVVLRAPRMRTVTNYFIVNLAIADILVIVFCLPATLIGNIFVP--WMLGWLMCKFVPYIQ 288
            |..:|.|:.|..:|..|||:.:.|||.:|:|:...|:|.|| ..:|.|  |:.|..:|.||..:|
 Frog    52 NYLLIYVICRTKKMHNVTNFLVGNLAFSDMLMCATCVPLTL-AYVFEPRGWVFGHFLCYFVFLMQ 115

  Fly   289 GVSVAASVYSLIAVSLDRFIAIWWPL-KQMTKRRARIMIIGIWVIALVTTIPWLLFFDLVPAEEV 352
            .|:|..||::|..:::||:.|..:|| :::|......::.|||:::.:...|
 Frog   116 PVTVYVSVFTLTVIAVDRYHATVYPLRRRLTIPTCAYILAGIWLLSCLMAAP------------- 167

  Fly   353 FSDALVSAY--SQPQF---LCQEVWPPGTDGNLYFLLANLVACYLLPMSLITLCYVLIWIKVSTR 412
               ||...|  ..||.   :|:|.|.......|.:..:.|:..|.||..:|.|.|:.|.:|:..|
 Frog   168 ---ALAHTYHVEFPQLDFSICEEFWFGMEKKRLAYAYSTLILTYALPFIIIALSYLRISVKLKNR 229

  Fly   413 SIPGE--SKDAQMDRMQQKSKVKVIKMLVAVVILFVLSWLPLYVIFARIKFGSDISQEEFEILKK 475
            .:||.  :..|:.||.::|   |..::||.||..|.:.||||::.  .|....||...:.:....
 Frog   230 VVPGNITNVQAEWDRARRK---KTFRLLVLVVGAFGMCWLPLHIF--NIMKDIDIHLIDKQYFNL 289

  Fly   476 VMPVAQWLGSSNSCINPILYS 496
            |..:..||...::|.|.:||:
 Frog   290 VQLLCHWLAMMSACTNSLLYA 310

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SIFaR	NP_650966.2	7tmA_CCKR-like	209..505	CDD:320124	90/298 (30%)
		TM helix 1	210..236	CDD:320124	8/25 (32%)
		TM helix 2	243..269	CDD:320124	11/25 (44%)
		TM helix 3	281..311	CDD:320124	12/29 (41%)
		TM helix 4	322..340	CDD:320124	3/17 (18%)
		TM helix 5	379..404	CDD:320124	8/24 (33%)
		TM helix 6	429..459	CDD:320124	11/29 (38%)
		TM helix 7	474..498	CDD:320124	7/23 (30%)
prlhr	XP_002940396.1	7tmA_PrRP_R	35..320	CDD:320516	90/300 (30%)
		TM helix 1	36..62	CDD:320516	8/27 (30%)
		TM helix 2	69..94	CDD:320516	11/25 (44%)
		TM helix 3	108..138	CDD:320516	12/29 (41%)
		TM helix 4	149..170	CDD:320516	5/36 (14%)
		TM helix 5	196..225	CDD:320516	9/28 (32%)
		TM helix 6	245..275	CDD:320516	12/34 (35%)
		TM helix 7	288..313	CDD:320516	7/23 (30%)