Protein Alignment SIFaR and cckar

DIOPT Version :10

• Sequence 1: NP_650966.2
• Gene: SIFaR / 42530
• FlyBaseID: FBgn0038880
• Length: 758
• Species: Drosophila melanogaster
• Sequence 2: XP_017945081.1
• Gene: cckar / 100492455
• XenbaseID: XB-GENE-992615
• Length: 432
• Species: Xenopus tropicalis
• Alignment Length: 389
• Identity: 114/389 - (29%)
• Similarity: 198/389 - (50%)
• Gaps: 77/389 - (19%)

  Fly   210 VYCVAYIVVFLVGLIGNSFVIAVVLRAPRMRTVTNYFIVNLAIADILVIVFCLPATLIGNIFVPW 274
            |..:.|.::||:.::|||.||||::|..|||||||.|:::||::|:::.:||:|.|||.|:...:
 Frog    47 VRILLYSLIFLLSVLGNSLVIAVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFTLIPNLLRDF 111

  Fly   275 MLGWLMCKFVPYIQGVSVAASVYSLIAVSLDRFIAIWWPLKQ---MTKRRARIMIIGIWVIALVT 336
            :.|..:||...|..|:||:.|.::|:|:||:|:.||..||:.   .||..|..:|...|.::...
 Frog   112 IFGSAVCKAATYFMGISVSVSTFNLVAISLERYSAICKPLQSRVWQTKSHALKVIAATWCLSFAI 176

  Fly   337 TIPWLLFFDLVPAEEVFSDALVSAYSQPQFLCQEVWPPG-TDGNLYFLLANLVACYLLPMSLITL 400
            ..|:.::..|||..::        .::...:|:.:||.. |..:.|..|  |:..:|:|..::|:
 Frog   177 MSPYPIYSTLVPLNKI--------QNRTANMCRLLWPSDLTQQSWYVFL--LLILFLVPGIVMTI 231

  Fly   401 CYVLIWIK------------------VST-----------RSIPGESK----------DAQMDRM 426
            .|.||.::                  :|:           :||....|          .|:::|:
 Frog   232 AYGLISMELYRGIKFEMSQRKERSSSISSNQFKNGDGCYLQSIKKRKKLEMHQLSSHHSAKIERV 296

  Fly   427 QQKS-------KVKVIKMLVAVVILFVLSWLPLYVIFARIKFGSDISQEEFEILKKVMPVA--QW 482
            :..|       |.:||:||:.:||||.:.|.|::...|...|.:|.:    :|....:|::  ..
 Frog   297 RSNSSAANLMAKKRVIRMLIVIVILFFICWTPVFSANAWRAFDTDSA----DISLSGVPISFIHL 357

  Fly   483 LGSSNSCINPILYS-VNKKYRRGFAAIIKSRSCC------GRLRYYDNVAIASSTTSTRKSSHY 539
            |..:::|:|||:|. :||::|.||.|..   :||      || |....||.....|:....|.|
 Frog   358 LSYTSACVNPIIYCFMNKRFRMGFLATF---TCCSSRGAQGR-RMVPGVADEEGRTTGASLSRY 417

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SIFaR	NP_650966.2	7tmA_CCKR-like	209..505	CDD:320124	101/347 (29%)
		TM helix 1	210..236	CDD:320124	11/25 (44%)
		TM helix 2	243..269	CDD:320124	12/25 (48%)
		TM helix 3	281..311	CDD:320124	13/29 (45%)
		TM helix 4	322..340	CDD:320124	3/17 (18%)
		TM helix 5	379..404	CDD:320124	7/24 (29%)
		TM helix 6	429..459	CDD:320124	13/36 (36%)
		TM helix 7	474..498	CDD:320124	7/26 (27%)
cckar	XP_017945081.1	7tmA_CCK-AR	46..381	CDD:320644	101/347 (29%)
		TM helix 1	47..73	CDD:320644	11/25 (44%)
		TM helix 2	80..106	CDD:320644	12/25 (48%)
		TM helix 3	118..148	CDD:320644	13/29 (45%)
		TM helix 4	161..182	CDD:320644	4/20 (20%)
		TM helix 5	210..239	CDD:320644	9/30 (30%)
		TM helix 6	306..336	CDD:320644	12/29 (41%)
		TM helix 7	349..374	CDD:320644	7/24 (29%)