Protein Alignment SIFaR and galr2

DIOPT Version :10

• Sequence 1: NP_650966.2
• Gene: SIFaR / 42530
• FlyBaseID: FBgn0038880
• Length: 758
• Species: Drosophila melanogaster
• Sequence 2: XP_002940025.1
• Gene: galr2 / 100486593
• XenbaseID: XB-GENE-921716
• Length: 373
• Species: Xenopus tropicalis
• Alignment Length: 370
• Identity: 105/370 - (28%)
• Similarity: 184/370 - (49%)
• Gaps: 57/370 - (15%)

  Fly   208 SMVYCVAYIVVFLVGLIGNSFVIAVVLRAPRMRTVTNYFIVNLAIADILVIVFCLPATLIGNIFV 272
            |::..|.|.::||||.:|||.|:||:||..::...||.||:||.:||:..|:||:|.........
 Frog    17 SVLIPVLYSLIFLVGTVGNSLVLAVLLRNGKVNNTTNLFILNLGVADLCFIIFCVPFQATIYTLD 81

  Fly   273 PWMLGWLMCKFVPYIQGVSVAASVYSLIAVSLDRFIAIWWPLKQ---MTKRRARIMIIGIWVIAL 334
            .|:.|..|||.|.:...:::.||.::|..|||||::||.:||:.   .|.:.|.:.|..||.::|
 Frog    82 SWVFGPFMCKAVHFFIYLTMYASSFTLTTVSLDRYLAIRYPLRSRELRTPKNALLAITLIWSLSL 146

  Fly   335 VTTIPWLLFF------DLVPAEEVFSDALVSAYSQPQFLCQEVWPPGTDGNLYFLLANLVACYLL 393
            |.:.|:|.::      :|.....|:.|    :|.:...||                 .....|::
 Frog   147 VFSGPYLSYYQEFQLSNLTVCHPVWQD----SYRRAMDLC-----------------TFAFSYVI 190

  Fly   394 PMSLITLCYV----LIWIKVSTRSIPGESKDAQMDRMQQKSKVKVIKMLVAVVILFVLSWLPLYV 454
            |:.:::|.|.    .:|..|.......|||         ::|.:|.:|::.|.:||.|.|||.::
 Frog   191 PVLILSLTYARTIRYLWTAVDPIEDMSESK---------RAKRRVTRMIIIVAVLFCLCWLPHHL 246

  Fly   455 IFARIKFGSDISQEEFEILKKVMPVAQWLGSSNSCINPILYS-VNKKYRRGFAAIIKSRSCCGRL 518
            :...:.||. .....|....:::  :..:..:|||:||::|: |:|.:|:||..|.:    |..|
 Frog   247 VILCVWFGY-FPLNNFTYALRIL--SHLVSYANSCVNPVVYALVSKHFRKGFRKIFR----CLLL 304

  Fly   519 RYYDNVAIASSTTSTRKSSHYHQNSSRKSPSSKGNAVSYIYEHNS 563
            |..     |::...|..::|... |:.:.|.::...:|..:.|.|
 Frog   305 RQR-----AANKVHTAPATHVGV-STHEGPCTEVTHISEGHLHCS 343

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SIFaR	NP_650966.2	7tmA_CCKR-like	209..505	CDD:320124	90/309 (29%)
		TM helix 1	210..236	CDD:320124	13/25 (52%)
		TM helix 2	243..269	CDD:320124	12/25 (48%)
		TM helix 3	281..311	CDD:320124	12/29 (41%)
		TM helix 4	322..340	CDD:320124	6/17 (35%)
		TM helix 5	379..404	CDD:320124	4/28 (14%)
		TM helix 6	429..459	CDD:320124	10/29 (34%)
		TM helix 7	474..498	CDD:320124	6/24 (25%)
galr2	XP_002940025.1	7tmA_Gal2_Gal3_R	18..295	CDD:320225	90/309 (29%)
		TM helix 1	19..45	CDD:320225	13/25 (52%)
		TM helix 2	52..78	CDD:320225	12/25 (48%)
		TM helix 3	90..120	CDD:320225	12/29 (41%)
		TM helix 4	132..152	CDD:320225	6/19 (32%)
		TM helix 5	176..205	CDD:320225	6/45 (13%)
		TM helix 6	221..251	CDD:320225	10/29 (34%)
		TM helix 7	263..288	CDD:320225	6/26 (23%)