Protein Alignment SIFaR and qrfpra

DIOPT Version :10

• Sequence 1: NP_650966.2
• Gene: SIFaR / 42530
• FlyBaseID: FBgn0038880
• Length: 758
• Species: Drosophila melanogaster
• Sequence 2: XP_021336543.1
• Gene: qrfpra / 100149491
• ZFINID: ZDB-GENE-090313-105
• Length: 422
• Species: Danio rerio
• Alignment Length: 348
• Identity: 110/348 - (31%)
• Similarity: 177/348 - (50%)
• Gaps: 59/348 - (16%)

  Fly   211 YCVAYIVVFLVGLIGNSFVIAVVLRAPRMRTVTNYFIVNLAIADILVIVFCLPATLIGNIFVPWM 275
            :.:.|.|:||:.|:|||.|:.:|||...::|.||.||.:||::|:|:..||:|.||:.||...|.
Zfish    48 FVIVYTVIFLLALVGNSVVVYIVLRKRGIQTATNIFICSLAVSDLLISFFCIPFTLLQNISSEWF 112

  Fly   276 LGWLMCKFVPYIQGVSVAASVYSLIAVSLDRFIAIWWPLK---QMTKRRARIMIIGIWVIALVTT 337
            .|.|:||.||::|..:|...:.::..::::|:..|..|||   |.|.:||..|:..:|:.|::..
Zfish   113 GGVLVCKTVPFVQTTAVVTGILTMTCIAVERYQGIVHPLKIKRQCTPQRAYRMLGVVWIAAMMVG 177

  Fly   338 IPWLLFFDLVPAEEVFSDALVSAYSQPQFLCQEVWPPGTDGNLY--FLLANLVACYLLPMSLITL 400
            .|.|....|    ||..|.|   |......|||.|........|  |:   ||..:|||::.:.:
Zfish   178 SPMLFVQQL----EVKYDFL---YDNHHVCCQERWRSSAHRKRYATFI---LVFLFLLPLAAMLI 232

  Fly   401 CYVLIWIKVSTRSIPGESKDAQMDRMQQKSKV-----KVIKMLVAVVILFVLSWLPLYVIFARIK 460
            .|..|.|::..|...|:|........::.||:     :.|||:|.:|:||.:.|.|.:.:  .|.
Zfish   233 LYTRIGIELWIRKQVGDSSVLNAMNQREVSKIARKKRRAIKMMVTIVVLFTVCWAPFHTV--HIL 295

  Fly   461 FGSDISQEEFEILKK---------VMPVAQWLGSSNSCINPILYS-VNKKYRRGFAAIIKSRSCC 515
            |       |:..|.|         ::.|||.:|.|||..|||:|: :|:.::         ::|.
Zfish   296 F-------EYSYLNKKYDDVTVNMIIAVAQAIGFSNSFNNPIIYAFMNENFQ---------KNCM 344

  Fly   516 GRLRYYDNVAIASSTTSTRKSSH 538
            ..|    :|.|       |:|||
Zfish   345 STL----SVCI-------RRSSH 356

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SIFaR	NP_650966.2	7tmA_CCKR-like	209..505	CDD:320124	102/313 (33%)
		TM helix 1	210..236	CDD:320124	11/24 (46%)
		TM helix 2	243..269	CDD:320124	13/25 (52%)
		TM helix 3	281..311	CDD:320124	7/29 (24%)
		TM helix 4	322..340	CDD:320124	4/17 (24%)
		TM helix 5	379..404	CDD:320124	8/26 (31%)
		TM helix 6	429..459	CDD:320124	11/34 (32%)
		TM helix 7	474..498	CDD:320124	12/33 (36%)
qrfpra	XP_021336543.1	7tmA_QRFPR	46..343	CDD:320333	102/322 (32%)
		TM helix 1	47..73	CDD:320333	11/24 (46%)
		TM helix 2	80..106	CDD:320333	13/25 (52%)
		TM helix 3	118..148	CDD:320333	7/29 (24%)
		TM helix 4	161..182	CDD:320333	6/20 (30%)
		TM helix 5	211..236	CDD:320333	8/27 (30%)
		TM helix 6	266..296	CDD:320333	10/31 (32%)
		TM helix 7	311..336	CDD:320333	11/24 (46%)