Protein Alignment CG3301 and RDH8

DIOPT Version :10

• Sequence 1: NP_650964.1
• Gene: CG3301 / 42528
• FlyBaseID: FBgn0038878
• Length: 250
• Species: Drosophila melanogaster
• Sequence 2: NP_056540.3
• Gene: RDH8 / 50700
• HGNCID: 14423
• Length: 311
• Species: Homo sapiens
• Alignment Length: 215
• Identity: 59/215 - (27%)
• Similarity: 91/215 - (42%)
• Gaps: 44/215 - (20%)

  Fly     7 RVAVVTGASAGIGAACCRDLVAKGMVVVGLARREK-------VLQDIKSSLPADQAA------RF 58
            |..:::|.|:|||..          :.|.||...|       .::|:......:.||      ..
Human     6 RTVLISGCSSGIGLE----------LAVQLAHDPKKRYQVVATMRDLGKKETLEAAAGEALGQTL 60

  Fly    59 HTRPCDVSNEQQVIDTFAWIDRTLGGADVLVNNAGIIRQMNITDPENSADVRA---ILDVNVLGV 120
            .....||.:::.|....:.|.   |..||||||||    |.:..|.....:.|   :.|.|..|.
Human    61 TVAQLDVCSDESVAQCLSCIQ---GEVDVLVNNAG----MGLVGPLEGLSLAAMQNVFDTNFFGA 118

  Fly   121 TWCTRQWFLSLQRRKVNDGHVVVINSVVGHSVPAVEGFSLN-MYAPSKHAITALTEILRQEFIKK 184
            ....:.....::||:  .||:|||:||:|     ::|...| :||.||.|:....|.|..:.::
Human   119 VRLVKAVLPGMKRRR--QGHIVVISSVMG-----LQGVIFNDVYAASKFALEGFFESLAIQLLQ- 175

  Fly   185 GTQTKITSISPGVVATEIFE 204
             ....|:.:.||.|.|| ||
Human   176 -FNIFISLVEPGPVVTE-FE 193

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3301	NP_650964.1	Rossmann-fold NAD(P)(+)-binding proteins	1..245	CDD:473865	59/215 (27%)
RDH8	NP_056540.3	type1_17beta-HSD-like_SDR_c	6..262	CDD:187666	59/215 (27%)