DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3301 and Dhrs11

DIOPT Version :9

Sequence 1:	NP_001287440.1	Gene:	CG3301 / 42528	FlyBaseID:	FBgn0038878	Length:	250	Species:	Drosophila melanogaster
Sequence 2:	XP_038942294.1	Gene:	Dhrs11 / 360583	RGDID:	1307935	Length:	299	Species:	Rattus norvegicus

Alignment Length:	249	Identity:	90/249 - (36%)
Similarity:	139/249 - (55%)	Gaps:	34/249 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MNRWLNRVAVVTGASAGIGAACCRDLVAKGMVVVGLARR----EKVLQDIKSSLPADQAARFHTR 61
            |.||.:|:|:|||||.|||||..|.||.:|:.|||.||.    |::..:.||   |.........
  Rat    76 MERWRDRLALVTGASGGIGAAVARALVQQGLKVVGCARTVGNIEELAAECKS---AGYPGTLIPY 137

  Fly    62 PCDVSNEQQVIDTFAWIDRTLGGADVLVNNAGIIRQMNITDPENSADVRAILDVNVLGVTWCTRQ 126
            .||:|||:.::..|:.:.....|.|:.:||||:.|..::.....|. .:.:.:||||.::.|||:
  Rat   138 RCDLSNEEDILSMFSAVRSQHSGVDICINNAGMARPDSLLSGSTSG-WKDMFNVNVLALSICTRE 201

  Fly   127 WFLSLQRRKVNDGHVVVINSVVGHSVPAVEGFSLNMYAPSKHAITALTEILRQEFIKKGTQTKIT 191
            .:.|::.|.|:|||::.|||:.||.||...  .::.|:.:|:|:|||||.||||.::..|..:.|
  Rat   202 AYQSMKERNVDDGHIININSMCGHRVPPQS--VIHFYSATKYAVTALTEGLRQELLEAQTHIRAT 264

  Fly   192 SISPGVVATEIFEAGSWEQPTGMPMLRSEDIADAVTYCIQTPPTVQIKELIIKP 245
                                    .||.||:|:||.|.:.|||.||:.::.::|
  Rat   265 ------------------------CLRPEDVAEAVIYVLSTPPHVQVGDIQMRP 294

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3301	NP_001287440.1	YdfG	1..250	CDD:226674	90/249 (36%)
CG3301	NP_001287440.1	NADB_Rossmann	1..245	CDD:304358	89/247 (36%)
Dhrs11	XP_038942294.1	Mgc4172-like_SDR_c	76..295	CDD:187601	90/249 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166337096
Domainoid	1	1.000	151	1.000	Domainoid score	I4244
eggNOG	1	0.900	-	-		E2759_KOG1205
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	188	1.000	Inparanoid score	I3811
OMA	1	1.010	-	-		QHG45743
OrthoDB	1	1.010	-	-		D1190834at2759
OrthoFinder	1	1.000	-	-		FOG0000588
OrthoInspector	1	1.000	-	-		otm44892
orthoMCL	1	0.900	-	-		OOG6_100320
Panther	1	1.100	-	-	O	PTHR43115
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X367
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.860