Protein Alignment CG3301 and HSD17B1

DIOPT Version :9

• Sequence 1: NP_001287440.1
• Gene: CG3301 / 42528
• FlyBaseID: FBgn0038878
• Length: 250
• Species: Drosophila melanogaster
• Sequence 2: NP_001317148.1
• Gene: HSD17B1 / 3292
• HGNCID: 5210
• Length: 329
• Species: Homo sapiens
• Alignment Length: 225
• Identity: 67/225 - (29%)
• Similarity: 98/225 - (43%)
• Gaps: 47/225 - (20%)

  Fly     8 VAVVTGASAGIGAACCRDLVAKGMVVVGLA----RREKV---LQDIKSSLPADQAAR-------- 57
            |.::||.|:|||.          .:.|.||    :..||   |:|:|:.....:|||
Human     5 VVLITGCSSGIGL----------HLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGS 59

  Fly    58 FHTRPCDVSNEQQVIDTFAWIDR-TLGGADVLVNNAGIIRQMNITDPENSAD---VRAILDVNVL 118
            ..|...||.:.:.|.   |..:| |.|..||||.|||    :.:..|..:..   |.::|||||:
Human    60 LETLQLDVRDSKSVA---AARERVTEGRVDVLVCNAG----LGLLGPLEALGEDAVASVLDVNVV 117

  Fly   119 GVTWCTRQWFLSLQRRKVNDGHVVVINSVVGHSVPAVEGFSLN-MYAPSKHAITALTEILRQEFI 182
            |.....:.:...::||  ..|.|:|..||.|     :.|...| :|..||.|:..|.|.|....:
Human   118 GTVRMLQAFLPDMKRR--GSGRVLVTGSVGG-----LMGLPFNDVYCASKFALEGLCESLAVLLL 175

  Fly   183 KKGTQTKITSISPGVVATEIFE--AGSWEQ 210
            ..|..: ::.|..|.|.|...|  .||.|:
Human   176 PFGVHS-LSLIECGPVHTAFMEKVLGSPEE 204

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3301	NP_001287440.1	YdfG	1..250	CDD:226674	67/225 (30%)
		NADB_Rossmann	1..245	CDD:304358	67/225 (30%)
HSD17B1	NP_001317148.1	NADB_Rossmann	4..262	CDD:304358	67/225 (30%)
		adh_short	5..198	CDD:278532	64/217 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	292..329

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1205
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900