DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG3301 and DHRS7C

DIOPT Version :9

Sequence 1:NP_001287440.1 Gene:CG3301 / 42528 FlyBaseID:FBgn0038878 Length:250 Species:Drosophila melanogaster
Sequence 2:NP_001207422.1 Gene:DHRS7C / 201140 HGNCID:32423 Length:312 Species:Homo sapiens


Alignment Length:261 Identity:62/261 - (23%)
Similarity:113/261 - (43%) Gaps:51/261 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly     6 NRVAVVTGASAGIGAACCRDLVAKGMVVVGLARREKVLQDIKSSL--PADQAARFHTR------- 61
            |:|.|:|.|.:|:|..|.|.....|..:|...:..:.|:::..:|  .||.:.:..|.       
Human    37 NKVVVITDAISGLGKECARVFHTGGARLVLCGKNWERLENLYDALISVADPSKQTFTPKLVLLDL 101

  Fly    62 ---PC--DVSNEQQVIDTFAWIDRTLGGADVLVNNAGIIRQMNITDPENSADV---RAILDVNVL 118
               .|  ||:.|  |:|.:       |..|:|:|||.:    .:..|.:...:   :.|:|.|..
Human   102 SDISCVPDVAKE--VLDCY-------GCVDILINNASV----KVKGPAHKISLELDKKIMDANYF 153

  Fly   119 GVTWCTRQWFLSLQRRKVNDGHVVVINSVVG-HSVPAVEGFSLNMYAPSKHAITALTEILRQEFI 182
            |....|:....::..|:.  |.:|::|::.| ..:|     ....||.||||.....:.||.|. 
Human   154 GPITLTKALLPNMISRRT--GQIVLVNNIQGKFGIP-----FRTTYAASKHAALGFFDCLRAEV- 210

  Fly   183 KKGTQTKITSISPGVVAT-EIF-EAGSWEQPTGMPMLRSEDIADAVTYCIQTPPTVQIKELIIKP 245
             :.....|:::||..:.: .:: |.|:||........|.      :||.:.   .|::.|.:::.
Human   211 -EEYDVVISTVSPTFIRSYHVYPEQGNWEASIWKFFFRK------LTYGVH---PVEVAEEVMRT 265

  Fly   246 V 246
            |
Human   266 V 266

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG3301NP_001287440.1 YdfG 1..250 CDD:226674 62/261 (24%)
NADB_Rossmann 1..245 CDD:304358 61/258 (24%)
DHRS7CNP_001207422.1 11beta-HSD1_like_SDR_c 35..297 CDD:187593 62/261 (24%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG1205
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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