Protein Alignment CG3301 and DHRS7C

DIOPT Version :10

• Sequence 1: NP_650964.1
• Gene: CG3301 / 42528
• FlyBaseID: FBgn0038878
• Length: 250
• Species: Drosophila melanogaster
• Sequence 2: NP_001207422.1
• Gene: DHRS7C / 201140
• HGNCID: 32423
• Length: 312
• Species: Homo sapiens
• Alignment Length: 261
• Identity: 62/261 - (23%)
• Similarity: 113/261 - (43%)
• Gaps: 51/261 - (19%)

  Fly     6 NRVAVVTGASAGIGAACCRDLVAKGMVVVGLARREKVLQDIKSSL--PADQAARFHTR------- 61
            |:|.|:|.|.:|:|..|.|.....|..:|...:..:.|:::..:|  .||.:.:..|.
Human    37 NKVVVITDAISGLGKECARVFHTGGARLVLCGKNWERLENLYDALISVADPSKQTFTPKLVLLDL 101

  Fly    62 ---PC--DVSNEQQVIDTFAWIDRTLGGADVLVNNAGIIRQMNITDPENSADV---RAILDVNVL 118
               .|  ||:.|  |:|.:       |..|:|:|||.:    .:..|.:...:   :.|:|.|..
Human   102 SDISCVPDVAKE--VLDCY-------GCVDILINNASV----KVKGPAHKISLELDKKIMDANYF 153

  Fly   119 GVTWCTRQWFLSLQRRKVNDGHVVVINSVVG-HSVPAVEGFSLNMYAPSKHAITALTEILRQEFI 182
            |....|:....::..|:.  |.:|::|::.| ..:|     ....||.||||.....:.||.|.
Human   154 GPITLTKALLPNMISRRT--GQIVLVNNIQGKFGIP-----FRTTYAASKHAALGFFDCLRAEV- 210

  Fly   183 KKGTQTKITSISPGVVAT-EIF-EAGSWEQPTGMPMLRSEDIADAVTYCIQTPPTVQIKELIIKP 245
             :.....|:::||..:.: .:: |.|:||........|.      :||.:.   .|::.|.:::.
Human   211 -EEYDVVISTVSPTFIRSYHVYPEQGNWEASIWKFFFRK------LTYGVH---PVEVAEEVMRT 265

  Fly   246 V 246
            |
Human   266 V 266

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3301	NP_650964.1	Rossmann-fold NAD(P)(+)-binding proteins	1..245	CDD:473865	61/258 (24%)
DHRS7C	NP_001207422.1	11beta-HSD1_like_SDR_c	35..297	CDD:187593	62/261 (24%)