Protein Alignment Idi and IDI2

DIOPT Version :9

• Sequence 1: NP_001163673.1
• Gene: Idi / 42526
• FlyBaseID: FBgn0038876
• Length: 256
• Species: Drosophila melanogaster
• Sequence 2: NP_150286.1
• Gene: IDI2 / 91734
• HGNCID: 23487
• Length: 227
• Species: Homo sapiens
• Alignment Length: 219
• Identity: 92/219 - (42%)
• Similarity: 137/219 - (62%)
• Gaps: 5/219 - (2%)

  Fly    40 DPLQAHALKEQCILVDANDQAIGAASKADCHRVHPETNDVKLHRAFSVFLFNSQGEMLVQKRSSH 104
            |..|...|:|..|:||.||:.|||.:|.:|| ::.......|||||||.|||::..:|:|:||..
Human    10 DRRQLQRLEEMLIVVDENDKVIGADTKRNCH-LNENIEKGLLHRAFSVVLFNTKNRILIQQRSDT 73

  Fly   105 KITFPNTYTNACCSHPLYEIEQERQERNAQGIRVAAQRRLNYELGIPTEELQPQDFRYLTRIHYA 169
            |:|||..:|::|.|||||. ..|.:|::|.|:|.||||||..|||||.|::.|:|..::|..|:.
Human    74 KVTFPGYFTDSCSSHPLYN-PAELEEKDAIGVRRAAQRRLQAELGIPGEQISPEDIVFMTIYHHK 137

  Fly   170 DTGDGVWGEHEIDYILFLQKDVTLRPNSNEVSEVRYLRRDKIDEAV---AKFSAPLTPWFSLILQ 231
            ...|.:||||||.|:|.::|:|||.|:.:|...:.||.::::.|.:   |:....:|||...|.:
Human   138 AKSDRIWGEHEICYLLLVRKNVTLNPDPSETKSILYLSQEELWELLEREARGEVKVTPWLRTIAE 202

  Fly   232 HRLKLWWDNLHQLEQFEDLSNIQR 255
            ..|..||.:|..:..|.:|..|.|
Human   203 RFLYRWWPHLDDVTPFVELHKIHR 226

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Idi	NP_001163673.1	Nudix_Hydrolase	48..256	CDD:294304	89/211 (42%)
		Idi	49..233	CDD:224360	81/186 (44%)
IDI2	NP_150286.1	Nudix_Hydrolase	6..227	CDD:320976	92/219 (42%)
		Microbody targeting signal. /evidence=ECO:0000255	225..227		1/2 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165159889
Domainoid	1	1.000	169	1.000	Domainoid score	I3809
eggNOG	1	0.900	-	-		E1_COG1443
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	219	1.000	Inparanoid score	I3581
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54285
OrthoDB	1	1.010	-	-		D1281908at2759
OrthoFinder	1	1.000	-	-		FOG0001381
OrthoInspector	1	1.000	-	-		otm41265
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10885
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X870
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	13	12.870