DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Idi and Idi1

DIOPT Version :9

Sequence 1:	NP_001163673.1	Gene:	Idi / 42526	FlyBaseID:	FBgn0038876	Length:	256	Species:	Drosophila melanogaster
Sequence 2:	NP_445991.2	Gene:	Idi1 / 89784	RGDID:	621835	Length:	283	Species:	Rattus norvegicus

Alignment Length:	252	Identity:	117/252 - (46%)
Similarity:	157/252 - (62%)	Gaps:	11/252 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LLPRVSWLRGCSTTAVGQ-KHQRQVPTEFAVH-DPLQAHALKEQCILVDANDQAIGAASKADCHR 71
            ||....|.| |   .:|| :|...:|...|.: |..|...|.|.|||:|.||..|||.:|.:||
  Rat    37 LLDTPLWNR-C---VLGQIRHSVTMPEINASNLDEKQVQLLAEMCILIDENDNKIGADTKKNCH- 96

  Fly    72 VHPETNDVKLHRAFSVFLFNSQGEMLVQKRSSHKITFPNTYTNACCSHPLYEIEQERQERNAQGI 136
            ::...:...:||||||||||::.::|:|:||..|||||..:||:||||||.. ..|.:|.:|.|:
  Rat    97 LNENIDKGLIHRAFSVFLFNTENKLLLQQRSDAKITFPGCFTNSCCSHPLNN-PGELEENDAMGV 160

  Fly   137 RVAAQRRLNYELGIPTEELQPQDFRYLTRIHYADTGDGVWGEHEIDYILFLQKDVTLRPNSNEVS 201
            :.||||||..|||||.||:...:..|||||:|....||:||||||||||||:|:|||.|:.||:.
  Rat   161 KRAAQRRLKAELGIPLEEVDLNEMNYLTRIYYKAQSDGIWGEHEIDYILFLRKNVTLNPDPNEIK 225

  Fly   202 EVRYLRRDKIDEAV---AKFSAPLTPWFSLILQHRLKLWWDNLHQLEQFEDLSNIQR 255
            ...|:.::::.|.:   |:....|||||.:|....|..|||||:.|..|.|...|.|
  Rat   226 SYCYVSKEELKEILKKEARGEIKLTPWFKIIADAFLFKWWDNLNHLSPFVDHEKIHR 282

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Idi	NP_001163673.1	Nudix_Hydrolase	48..256	CDD:294304	104/211 (49%)
Idi	NP_001163673.1	Idi	49..233	CDD:224360	93/186 (50%)
Idi1	NP_445991.2	Nudix_Hydrolase	56..283	CDD:294304	109/229 (48%)
Idi1	NP_445991.2	Idi	75..278	CDD:224360	102/204 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166353954
Domainoid	1	1.000	165	1.000	Domainoid score	I3816
eggNOG	1	0.900	-	-		E1_COG1443
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3315
Inparanoid	1	1.050	214	1.000	Inparanoid score	I3543
OMA	1	1.010	-	-		QHG54285
OrthoDB	1	1.010	-	-		D1281908at2759
OrthoFinder	1	1.000	-	-		FOG0001381
OrthoInspector	1	1.000	-	-		otm45394
orthoMCL	1	0.900	-	-		OOG6_102471
Panther	1	1.100	-	-	LDO	PTHR10885
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X870
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770