DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Idi and idi1

DIOPT Version :9

Sequence 1:	NP_001163673.1	Gene:	Idi / 42526	FlyBaseID:	FBgn0038876	Length:	256	Species:	Drosophila melanogaster
Sequence 2:	XP_005162565.1	Gene:	idi1 / 553513	ZFINID:	ZDB-GENE-050913-44	Length:	278	Species:	Danio rerio

Alignment Length:	219	Identity:	110/219 - (50%)
Similarity:	147/219 - (67%)	Gaps:	5/219 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 DPLQAHALKEQCILVDANDQAIGAASKADCHRVHPETNDVKLHRAFSVFLFNSQGEMLVQKRSSH 104
            |..|...|.|.|||:|.||:.|||.||.:|| ::...:...||||||||||||:.::|:|:||..
Zfish    61 DEKQVQLLAEMCILIDENDKKIGADSKKNCH-LNSNIDKGLLHRAFSVFLFNSEEKLLLQQRSDA 124

  Fly   105 KITFPNTYTNACCSHPLYEIEQERQERNAQGIRVAAQRRLNYELGIPTEELQPQDFRYLTRIHYA 169
            |||||..:||.||||||: ...|.:|::|.|:|.||||||..|||||.:::.|::..|||||||.
Zfish   125 KITFPGCFTNTCCSHPLH-TTSELEEQDAIGVRRAAQRRLQAELGIPMDQVLPEEMTYLTRIHYK 188

  Fly   170 DTGDGVWGEHEIDYILFLQKDVTLRPNSNEVSEVRYLRRDKIDEAVAKFSAP---LTPWFSLILQ 231
            ...||||||||||||:|:||||.|.|:.||:....|:.::::.|.:.|....   :|||||||.:
Zfish   189 AQSDGVWGEHEIDYIIFMQKDVDLNPDPNEIQSHCYVSKEELKEILEKAKRKELLITPWFSLIAE 253

  Fly   232 HRLKLWWDNLHQLEQFEDLSNIQR 255
            ..|..||:||..|:.|.:...|.|
Zfish   254 TFLFKWWENLRNLKPFIEHDRIHR 277

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Idi	NP_001163673.1	Nudix_Hydrolase	48..256	CDD:294304	107/211 (51%)
Idi	NP_001163673.1	Idi	49..233	CDD:224360	98/186 (53%)
idi1	XP_005162565.1	Nudix_Hydrolase	49..278	CDD:294304	110/219 (50%)
idi1	XP_005162565.1	Idi	70..259	CDD:224360	99/190 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170596156
Domainoid	1	1.000	165	1.000	Domainoid score	I3889
eggNOG	1	0.900	-	-		E1_COG1443
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3315
Inparanoid	1	1.050	220	1.000	Inparanoid score	I3545
OMA	1	1.010	-	-		QHG54285
OrthoDB	1	1.010	-	-		D1281908at2759
OrthoFinder	1	1.000	-	-		FOG0001381
OrthoInspector	1	1.000	-	-		oto39234
orthoMCL	1	0.900	-	-		OOG6_102471
Panther	1	1.100	-	-	LDO	PTHR10885
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R587
SonicParanoid	1	1.000	-	-		X870
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800