Protein Alignment Idi and IDI1

DIOPT Version :10

• Sequence 1: NP_650962.1
• Gene: Idi / 42526
• FlyBaseID: FBgn0038876
• Length: 256
• Species: Drosophila melanogaster
• Sequence 2: NP_004499.2
• Gene: IDI1 / 3422
• HGNCID: 5387
• Length: 284
• Species: Homo sapiens
• Alignment Length: 219
• Identity: 109/219 - (49%)
• Similarity: 144/219 - (65%)
• Gaps: 5/219 - (2%)

  Fly    40 DPLQAHALKEQCILVDANDQAIGAASKADCHRVHPETNDVKLHRAFSVFLFNSQGEMLVQKRSSH 104
            |..|...|.|.|||:|.||..|||.:|.:|| ::.......|||||||||||::.::|:|:||..
Human    67 DKQQVQLLAEMCILIDENDNKIGAETKKNCH-LNENIEKGLLHRAFSVFLFNTENKLLLQQRSDA 130

  Fly   105 KITFPNTYTNACCSHPLYEIEQERQERNAQGIRVAAQRRLNYELGIPTEELQPQDFRYLTRIHYA 169
            |||||..:||.||||||.. ..|.:|.:|.|:|.||||||..|||||.||:.|::..|||||||.
Human   131 KITFPGCFTNTCCSHPLSN-PAELEESDALGVRRAAQRRLKAELGIPLEEVPPEEINYLTRIHYK 194

  Fly   170 DTGDGVWGEHEIDYILFLQKDVTLRPNSNEVSEVRYLRRDKIDEAVAKFSA---PLTPWFSLILQ 231
            ...||:||||||||||.::|:|||.|:.||:....|:.::::.|.:.|.::   .:||||.:|..
Human   195 AQSDGIWGEHEIDYILLVRKNVTLNPDPNEIKSYCYVSKEELKELLKKAASGEIKITPWFKIIAA 259

  Fly   232 HRLKLWWDNLHQLEQFEDLSNIQR 255
            ..|..|||||:.|.||.|...|.|
Human   260 TFLFKWWDNLNHLNQFVDHEKIYR 283

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Idi	NP_650962.1	NUDIX_Hydrolase	48..256	CDD:469772	106/211 (50%)
IDI1	NP_004499.2	NUDIX_Hydrolase	78..284	CDD:469772	105/208 (50%)