Protein Alignment AP-2sigma and AP1S2

DIOPT Version :10

• Sequence 1: NP_650961.2
• Gene: AP-2sigma / 42525
• FlyBaseID: FBgn0043012
• Length: 142
• Species: Drosophila melanogaster
• Sequence 2: NP_001259000.1
• Gene: AP1S2 / 8905
• HGNCID: 560
• Length: 160
• Species: Homo sapiens
• Alignment Length: 134
• Identity: 65/134 - (48%)
• Similarity: 94/134 - (70%)
• Gaps: 0/134 - (0%)

  Fly     2 IRFILIQNRAGKTRLAKWYMNFDDDEKQKLIEEVHAVVTVRDAKHTNFVEFRNFKIVYRRYAGLY 66
            ::|:|:.:|.||.||.|||:...|.||:|:..|:...|..|..|..:|:|:|:.||||:|||.||
Human     1 MQFMLLFSRQGKLRLQKWYVPLSDKEKKKITRELVQTVLARKPKMCSFLEWRDLKIVYKRYASLY 65

  Fly    67 FCICVDVNDNNLCYLEAIHNFVEVLNEYFHNVCELDLVFNFYKVYSVVDEMFLAGEIRETSQTKV 131
            ||..::..||.|..||.||.:||:|::||.:|||||::|||.|.|.::||..|.||::|||:..|
Human    66 FCCAIEDQDNELITLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLLGGEVQETSKKNV 130

  Fly   132 LKQL 135
            ||.:
Human   131 LKAI 134

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AP-2sigma	NP_650961.2	AP2_sigma	1..141	CDD:341437	65/134 (49%)
AP1S2	NP_001259000.1	AP1_sigma	2..144	CDD:341435	65/133 (49%)