Protein Alignment AP-2sigma and AP1S3

DIOPT Version :10

• Sequence 1: NP_650961.2
• Gene: AP-2sigma / 42525
• FlyBaseID: FBgn0043012
• Length: 142
• Species: Drosophila melanogaster
• Sequence 2: NP_001034658.1
• Gene: AP1S3 / 130340
• HGNCID: 18971
• Length: 154
• Species: Homo sapiens
• Alignment Length: 135
• Identity: 61/135 - (45%)
• Similarity: 94/135 - (69%)
• Gaps: 0/135 - (0%)

  Fly     1 MIRFILIQNRAGKTRLAKWYMNFDDDEKQKLIEEVHAVVTVRDAKHTNFVEFRNFKIVYRRYAGL 65
            ||.|||:.:|.||.||.|||:...|.|::|:..|:..::..|..:.::||:::..|:||:|||.|
Human     1 MIHFILLFSRQGKLRLQKWYITLPDKERKKITREIVQIILSRGHRTSSFVDWKELKLVYKRYASL 65

  Fly    66 YFCICVDVNDNNLCYLEAIHNFVEVLNEYFHNVCELDLVFNFYKVYSVVDEMFLAGEIRETSQTK 130
            |||..::..||.|..||.:|.:||:|::||.||||||::|||.|.|.::||..:.|||:|||:..
Human    66 YFCCAIENQDNELLTLEIVHRYVELLDKYFGNVCELDIIFNFEKAYFILDEFIIGGEIQETSKKI 130

  Fly   131 VLKQL 135
            .:|.:
Human   131 AVKAI 135

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AP-2sigma	NP_650961.2	AP2_sigma	1..141	CDD:341437	61/135 (45%)
AP1S3	NP_001034658.1	AP1_sigma	3..143	CDD:341435	59/133 (44%)