Protein Alignment AP-2sigma and AP3S2

DIOPT Version :10

• Sequence 1: NP_650961.2
• Gene: AP-2sigma / 42525
• FlyBaseID: FBgn0043012
• Length: 142
• Species: Drosophila melanogaster
• Sequence 2: NP_005820.1
• Gene: AP3S2 / 10239
• HGNCID: 571
• Length: 193
• Species: Homo sapiens
• Alignment Length: 148
• Identity: 56/148 - (37%)
• Similarity: 91/148 - (61%)
• Gaps: 6/148 - (4%)

  Fly     1 MIRFILIQNRAGKTRLAKWYMNFDDDEKQKLIEEVHAVVTVRDAKHTNFVE------FRNFKIVY 59
            ||:.||:.|..||.||.::|..|.::.:|:::.|...:|..||....||:|      ..::|::|
Human     1 MIQAILVFNNHGKPRLVRFYQRFPEEIQQQIVRETFHLVLKRDDNICNFLEGGSLIGGSDYKLIY 65

  Fly    60 RRYAGLYFCICVDVNDNNLCYLEAIHNFVEVLNEYFHNVCELDLVFNFYKVYSVVDEMFLAGEIR 124
            |.||.|||..|||.:::.|..|:.|..|||.|::.|.|||||||:|:..||:.::.|:.:.|.:.
Human    66 RHYATLYFVFCVDSSESELGILDLIQVFVETLDKCFENVCELDLIFHMDKVHYILQEVVMGGMVL 130

  Fly   125 ETSQTKVLKQLLTLNSLE 142
            ||:..:::.|:...|.||
Human   131 ETNMNEIVAQIEAQNRLE 148

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AP-2sigma	NP_650961.2	AP2_sigma	1..141	CDD:341437	54/145 (37%)
AP3S2	NP_005820.1	AP3_sigma	1..146	CDD:341438	53/144 (37%)