Protein Alignment AP-2sigma and ARPIN-AP3S2

DIOPT Version :9

• Sequence 1: NP_650961.2
• Gene: AP-2sigma / 42525
• FlyBaseID: FBgn0043012
• Length: 142
• Species: Drosophila melanogaster
• Sequence 2: NP_001185987.1
• Gene: ARPIN-AP3S2 / 100526783
• HGNCID: 38824
• Length: 394
• Species: Homo sapiens
• Alignment Length: 162
• Identity: 53/162 - (32%)
• Similarity: 84/162 - (51%)
• Gaps: 32/162 - (19%)

  Fly    12 GKTRLAKWYMNF--------------------DDDE-----KQKLIEEVHAVVTVRDAKHTNFVE 51
            |||. |.|..|.                    :|:|     :|:::.|...:|..||....||:|
Human   189 GKTG-ASWTDNIMAQKCSKGAAAEIREQGDGAEDEEWPEEIQQQIVRETFHLVLKRDDNICNFLE 252

  Fly    52 ------FRNFKIVYRRYAGLYFCICVDVNDNNLCYLEAIHNFVEVLNEYFHNVCELDLVFNFYKV 110
                  ..::|::||.||.|||..|||.:::.|..|:.|..|||.|::.|.|||||||:|:..||
Human   253 GGSLIGGSDYKLIYRHYATLYFVFCVDSSESELGILDLIQVFVETLDKCFENVCELDLIFHMDKV 317

  Fly   111 YSVVDEMFLAGEIRETSQTKVLKQLLTLNSLE 142
            :.::.|:.:.|.:.||:..:::.|:...|.||
Human   318 HYILQEVVMGGMVLETNMNEIVAQIEAQNRLE 349

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AP-2sigma	NP_650961.2	AP2_sigma	1..141	CDD:341437	51/159 (32%)
ARPIN-AP3S2	NP_001185987.1	UPF0552	1..224	CDD:287536	7/35 (20%)
		APS2	226..349	CDD:227363	43/122 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5030
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900