Protein Alignment Rab1 and Rab35

DIOPT Version :10

• Sequence 1: NP_732610.1
• Gene: Rab1 / 42524
• FlyBaseID: FBgn0285937
• Length: 205
• Species: Drosophila melanogaster
• Sequence 2: NP_937806.1
• Gene: Rab35 / 77407
• MGIID: 1924657
• Length: 201
• Species: Mus musculus
• Alignment Length: 205
• Identity: 114/205 - (55%)
• Similarity: 145/205 - (70%)
• Gaps: 13/205 - (6%)

  Fly     7 EYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQE 71
            :||:|||||:|||||||||.|||||||:|::.|||:||||||||||:|::|:.:|||||||||||
Mouse     4 DYDHLFKLLIIGDSGVGKSSLLLRFADNTFSGSYITTIGVDFKIRTVEINGEKVKLQIWDTAGQE 68

  Fly    72 RFRTITSSYYRGAHGIIVVYDCTDQESFNNVKQWLEEIERYACENVNKLLVGNKSDLTTKKVVDH 136
            |||||||:||||.||:|||||.|..|||.|||:||.||.: .|::|.::|||||:|...:|||:.
Mouse    69 RFRTITSTYYRGTHGVIVVYDVTSAESFVNVKRWLHEINQ-NCDDVCRILVGNKNDDPERKVVET 132

  Fly   137 TTAAEYAAQLGIPFLETSAKSATNVEQAFMTMAAEIKNRVGPPSSATDNASKVKIDQGRPV---- 197
            ..|.::|.|:||...|||||...|||:.| ....|:..|     :..||.:|.:..|...|
Mouse   133 EDAYKFAGQMGIQLFETSAKENVNVEEMF-NCITELVLR-----AKKDNLAKQQQQQQNDVVKLT 191

  Fly   198 --ENTKSGCC 205
              ...|..||
Mouse   192 KNSKRKKRCC 201

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab1	NP_732610.1	Rab1_Ypt1	10..175	CDD:206661	103/164 (63%)
Rab35	NP_937806.1	Rab35	3..201	CDD:133310	112/203 (55%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:Q15286	30..42		6/11 (55%)
		Effector region. /evidence=ECO:0000250	37..45		6/7 (86%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:Q15286	64..80		14/15 (93%)