DRSC/TRiP Functional Genomics Resources

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Protein Alignment Rab1 and Rab1b

DIOPT Version :9

Sequence 1:NP_732610.1 Gene:Rab1 / 42524 FlyBaseID:FBgn0285937 Length:205 Species:Drosophila melanogaster
Sequence 2:NP_083852.1 Gene:Rab1b / 76308 MGIID:1923558 Length:201 Species:Mus musculus


Alignment Length:202 Identity:167/202 - (82%)
Similarity:181/202 - (89%) Gaps:1/202 - (0%)


- Green bases have known domain annotations that are detailed below.


  Fly     4 VNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTA 68
            :||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse     1 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTA 65

  Fly    69 GQERFRTITSSYYRGAHGIIVVYDCTDQESFNNVKQWLEEIERYACENVNKLLVGNKSDLTTKKV 133
            ||||||||||||||||||||||||.|||||:.||||||:||:|||.|||||||||||||||||||
Mouse    66 GQERFRTITSSYYRGAHGIIVVYDVTDQESYANVKQWLQEIDRYASENVNKLLVGNKSDLTTKKV 130

  Fly   134 VDHTTAAEYAAQLGIPFLETSAKSATNVEQAFMTMAAEIKNRVGPPSSATDNASKVKIDQGRPVE 198
            ||:|||.|:|..||:||||||||:||||||||||||||||.|:||.:::......:||| ..||:
Mouse   131 VDNTTAKEFADSLGVPFLETSAKNATNVEQAFMTMAAEIKKRMGPGAASGGERPNLKID-STPVK 194

  Fly   199 NTKSGCC 205
            ....|||
Mouse   195 PASGGCC 201

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Rab1NP_732610.1 Rab1_Ypt1 10..175 CDD:206661 151/164 (92%)
Rab1bNP_083852.1 Rab1_Ypt1 7..172 CDD:206661 151/164 (92%)
Effector region. /evidence=ECO:0000255 37..45 7/7 (100%)
Switch 2 region, required for interaction with REP1/CHM. /evidence=ECO:0000250|UniProtKB:Q9H0U4 64..83 18/18 (100%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 174..201 8/27 (30%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 297 1.000 Domainoid score I1460
eggNOG 1 0.900 - - E1_KOG0084
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 341 1.000 Inparanoid score I2339
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1149105at2759
OrthoFinder 1 1.000 - - FOG0001193
OrthoInspector 1 1.000 - - otm43075
orthoMCL 1 0.900 - - OOG6_101123
Panther 1 1.100 - - O PTHR24073
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R1997
SonicParanoid 1 1.000 - - X737
SwiftOrtho 1 1.000 - -
TreeFam 1 0.960 - -
1413.860

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