DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab1 and rab43

DIOPT Version :9

Sequence 1:	NP_732610.1	Gene:	Rab1 / 42524	FlyBaseID:	FBgn0285937	Length:	205	Species:	Drosophila melanogaster
Sequence 2:	NP_001038812.1	Gene:	rab43 / 751627	ZFINID:	ZDB-GENE-060825-25	Length:	208	Species:	Danio rerio

Alignment Length:	198	Identity:	90/198 - (45%)
Similarity:	130/198 - (65%)	Gaps:	2/198 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 YDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQER 72
            ||.:||::|:||.||||:|::.||....:.|...:||||||.::|:|:.||.:||||||||||||
Zfish    10 YDLVFKIVLVGDVGVGKTCVVQRFKTGIFIEKQGNTIGVDFTMKTLEIHGKRVKLQIWDTAGQER 74

  Fly    73 FRTITSSYYRGAHGIIVVYDCTDQESFNNVKQWLEEIERYACENVNKLLVGNKSDLTTKKVVDHT 137
            |||||.||||.|:|.|:.||.|.:.:|.:|.:|:|::::|...|:..||:|||.||:..:.|...
Zfish    75 FRTITQSYYRSANGAIITYDITKKATFLSVPKWMEDVKKYGGSNIVPLLIGNKCDLSESREVPLE 139

  Fly   138 TAAEYAAQLG-IPFLETSAKSATNVEQAFMTMAAEIKNRVGPPSSATDNASKVKIDQGRPVENTK 201
            .|...|.||. :..:|||||.::||::||..||:|:..|.|.|....:.....|: .|:.|....
Zfish   140 DAQTMAHQLDFVSAIETSAKDSSNVDEAFNKMASELILRHGGPMFTENVTDSFKL-TGKDVAGEG 203

  Fly   202 SGC 204
            .||
Zfish   204 WGC 206

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab1	NP_732610.1	Rab1_Ypt1	10..175	CDD:206661	80/165 (48%)
rab43	NP_001038812.1	P-loop_NTPase	11..175	CDD:304359	80/163 (49%)
rab43	NP_001038812.1	RAB	14..178	CDD:197555	80/163 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0084
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1149105at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820