DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab1 and Rab3b

DIOPT Version :9

Sequence 1:	NP_732610.1	Gene:	Rab1 / 42524	FlyBaseID:	FBgn0285937	Length:	205	Species:	Drosophila melanogaster
Sequence 2:	NP_076026.1	Gene:	Rab3b / 69908	MGIID:	1917158	Length:	219	Species:	Mus musculus

Alignment Length:	202	Identity:	92/202 - (45%)
Similarity:	132/202 - (65%)	Gaps:	6/202 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 YDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQER 72
            :||:||||:||:|.|||:..|.|:||||:|.:::||:|:|||::|:....|.:||||||||||||
Mouse    19 FDYMFKLLIIGNSSVGKTSFLFRYADDTFTPAFVSTVGIDFKVKTVYRHEKRVKLQIWDTAGQER 83

  Fly    73 FRTITSSYYRGAHGIIVVYDCTDQESFNNVKQWLEEIERYACENVNKLLVGNKSDLTTKKVVDHT 137
            :||||::|||||.|.|::||.|::||||.|:.|..:|:.|:.:|...:|||||.|:..::||...
Mouse    84 YRTITTAYYRGAMGFILMYDITNEESFNAVQDWATQIKTYSWDNAQVILVGNKCDMEEERVVPTE 148

  Fly   138 TAAEYAAQLGIPFLETSAKSATNVEQAFMTMAAEIKNRVGPPSSATD----NASK-VKIDQGRPV 197
            .....|.|||..|.|.|||...:|.|||..:...|.:::. .|..||    .||| .::....|:
Mouse   149 KGRLLAEQLGFDFFEASAKENISVRQAFERLVDAICDKMS-DSMDTDPSVLGASKTTRLSDTPPL 212

  Fly   198 ENTKSGC 204
            ......|
Mouse   213 LQQNCSC 219

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab1	NP_732610.1	Rab1_Ypt1	10..175	CDD:206661	83/164 (51%)
Rab3b	NP_076026.1	Rab3	22..186	CDD:206657	82/163 (50%)
Rab3b	NP_076026.1	Effector region. /evidence=ECO:0000250	51..59		3/7 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910