Protein Alignment Rab1 and Rab2a

DIOPT Version :10

• Sequence 1: NP_732610.1
• Gene: Rab1 / 42524
• FlyBaseID: FBgn0285937
• Length: 205
• Species: Drosophila melanogaster
• Sequence 2: NP_001398756.1
• Gene: Rab2a / 59021
• MGIID: 1928750
• Length: 216
• Species: Mus musculus
• Alignment Length: 198
• Identity: 90/198 - (45%)
• Similarity: 127/198 - (64%)
• Gaps: 22/198 - (11%)

  Fly     8 YDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQER 72
            |.||||.::|||:|||||||||:|.|..:...:..||||:|..|.|.:|||.||||||||||||.
Mouse     3 YAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQES 67

  Fly    73 FRTITSSYYRGAHGIIVVYDCTDQESFNNVKQWLEEIERYACENVNKLLVGNKSDLTTKKVVDHT 137
            ||:||.||||||.|.::|||.|.:::||::..|||:..:::..|:..:|:||||||.:::.|...
Mouse    68 FRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNKSDLESRREVKKE 132

  Fly   138 TAAEYAAQLGIPFLETSAKSATNVEQAFMTMAAEIKNRVGPPSSATDNASKVKIDQGRPVENTKS 202
            ....:|.:.|:.|:|||||:|:|||:   .|.||               |.|:::..:..    .
Mouse   133 EGEAFAREHGLIFMETSAKTASNVEE---VMNAE---------------STVQMNHCQDA----G 175

  Fly   203 GCC 205
            |||
Mouse   176 GCC 178

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab1	NP_732610.1	Rab1_Ypt1	10..175	CDD:206661	84/164 (51%)
Rab2a	NP_001398756.1	Required for interaction with PRKCI. /evidence=ECO:0000250	2..19		10/15 (67%)
		Rab2	3..158	CDD:206658	81/154 (53%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P61106	37..42		3/4 (75%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P61106	63..72		6/8 (75%)