Protein Alignment Rab1 and RAB5C

DIOPT Version :10

• Sequence 1: NP_732610.1
• Gene: Rab1 / 42524
• FlyBaseID: FBgn0285937
• Length: 205
• Species: Drosophila melanogaster
• Sequence 2: NP_001238968.1
• Gene: RAB5C / 5878
• HGNCID: 9785
• Length: 249
• Species: Homo sapiens
• Alignment Length: 198
• Identity: 85/198 - (42%)
• Similarity: 122/198 - (61%)
• Gaps: 9/198 - (4%)

  Fly    12 FKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTI 76
            |||:|:|:|.||||.|:|||....:.|...||||..|..:|:.||..|:|.:|||||||||:.::
Human    55 FKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQTVCLDDTTVKFEIWDTAGQERYHSL 119

  Fly    77 TSSYYRGAHGIIVVYDCTDQESFNNVKQWLEEIERYACENVNKLLVGNKSDLTTKKVVDHTTAAE 141
            ...|||||...|||||.|:.::|...|.|::|::|.|..|:...|.|||:||.:|:.|:...|..
Human   120 APMYYRGAQAAIVVYDITNTDTFARAKNWVKELQRQASPNIVIALAGNKADLASKRAVEFQEAQA 184

  Fly   142 YAAQLGIPFLETSAKSATNVEQAFMTMAAEI-KNRVGPPSSATDNASK---VKIDQGRPVENTKS 202
            ||....:.|:|||||:|.||.:.||.:|.:: ||.   |.:||....:   |.:.:..|.  ::|
Human   185 YADDNSLLFMETSAKTAMNVNEIFMAIAKKLPKNE---PQNATGAPGRNRGVDLQENNPA--SRS 244

  Fly   203 GCC 205
            .||
Human   245 QCC 247

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab1	NP_732610.1	Rab1_Ypt1	10..175	CDD:206661	76/163 (47%)
RAB5C	NP_001238968.1	Rab5_related	54..216	CDD:206653	75/160 (47%)