DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab1 and RAB13

DIOPT Version :9

Sequence 1:	NP_732610.1	Gene:	Rab1 / 42524	FlyBaseID:	FBgn0285937	Length:	205	Species:	Drosophila melanogaster
Sequence 2:	NP_002861.1	Gene:	RAB13 / 5872	HGNCID:	9762	Length:	203	Species:	Homo sapiens

Alignment Length:	190	Identity:	102/190 - (53%)
Similarity:	140/190 - (73%)	Gaps:	9/190 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 YDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQER 72
            ||:||||||||||||||:||::|||:|.:..:||||||:||||||::::||.||||:||||||||
Human     5 YDHLFKLLLIGDSGVGKTCLIIRFAEDNFNNTYISTIGIDFKIRTVDIEGKKIKLQVWDTAGQER 69

  Fly    73 FRTITSSYYRGAHGIIVVYDCTDQESFNNVKQWLEEIERYACENVNKLLVGNKSDLTTKKVVDHT 137
            |:|||::|||||.|||:|||.||::||.|::.|::.|:..|...|.:||:|||.|:..|:.|...
Human    70 FKTITTAYYRGAMGIILVYDITDEKSFENIQNWMKSIKENASAGVERLLLGNKCDMEAKRKVQKE 134

  Fly   138 TAAEYAAQLGIPFLETSAKSATNVEQAFMTMAAEIKNRVG---------PPSSATDNASK 188
            .|.:.|.:.||.|.||||||:.||::||.::|.:|..:.|         |||:......|
Human   135 QADKLAREHGIRFFETSAKSSMNVDEAFSSLARDILLKSGGRRSGNGNKPPSTDLKTCDK 194

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab1	NP_732610.1	Rab1_Ypt1	10..175	CDD:206661	95/164 (58%)
RAB13	NP_002861.1	Rab8_Rab10_Rab13_like	6..172	CDD:206659	96/165 (58%)
		Effector region. /evidence=ECO:0000250	37..45		6/7 (86%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	173..203		5/22 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910