Protein Alignment Rab1 and RAB5B

DIOPT Version :10

• Sequence 1: NP_732610.1
• Gene: Rab1 / 42524
• FlyBaseID: FBgn0285937
• Length: 205
• Species: Drosophila melanogaster
• Sequence 2: NP_001401387.1
• Gene: RAB5B / 5869
• HGNCID: 9784
• Length: 296
• Species: Homo sapiens
• Alignment Length: 199
• Identity: 83/199 - (41%)
• Similarity: 120/199 - (60%)
• Gaps: 11/199 - (5%)

  Fly    12 FKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTI 76
            |||:|:|:|.||||.|:|||....:.|...||||..|..:::.||..|:|.:|||||||||:.::
Human   102 FKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQSVCLDDTTVKFEIWDTAGQERYHSL 166

  Fly    77 TSSYYRGAHGIIVVYDCTDQESFNNVKQWLEEIERYACENVNKLLVGNKSDLTTKKVVDHTTAAE 141
            ...|||||...|||||.|:||:|...|.|::|::|.|..::...|.|||:||..|::|::..|..
Human   167 APMYYRGAQAAIVVYDITNQETFARAKTWVKELQRQASPSIVIALAGNKADLANKRMVEYEEAQA 231

  Fly   142 YAAQLGIPFLETSAKSATNVEQAFMTMAAEIKNRVGPPSSATDN----ASKVK-IDQGRPVENTK 201
            ||....:.|:|||||:|.||...|:.:|.::      |.|...|    |.:.: :|.....:..|
Human   232 YADDNSLLFMETSAKTAMNVNDLFLAIAKKL------PKSEPQNLGGAAGRSRGVDLHEQSQQNK 290

  Fly   202 SGCC 205
            |.||
Human   291 SQCC 294

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab1	NP_732610.1	Rab1_Ypt1	10..175	CDD:206661	74/162 (46%)
RAB5B	NP_001401387.1	Rab5_related	101..263	CDD:206653	74/166 (45%)