Protein Alignment Rab1 and RAB3B

DIOPT Version :10

• Sequence 1: NP_732610.1
• Gene: Rab1 / 42524
• FlyBaseID: FBgn0285937
• Length: 205
• Species: Drosophila melanogaster
• Sequence 2: NP_002858.2
• Gene: RAB3B / 5865
• HGNCID: 9778
• Length: 219
• Species: Homo sapiens
• Alignment Length: 202
• Identity: 89/202 - (44%)
• Similarity: 131/202 - (64%)
• Gaps: 6/202 - (2%)

  Fly     8 YDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQER 72
            :||:||||:||:|.|||:..|.|:||||:|.:::||:|:|||::|:....|.:||||||||||||
Human    19 FDYMFKLLIIGNSSVGKTSFLFRYADDTFTPAFVSTVGIDFKVKTVYRHEKRVKLQIWDTAGQER 83

  Fly    73 FRTITSSYYRGAHGIIVVYDCTDQESFNNVKQWLEEIERYACENVNKLLVGNKSDLTTKKVVDHT 137
            :||||::|||||.|.|::||.|::||||.|:.|..:|:.|:.:|...:|||||.|:..::||...
Human    84 YRTITTAYYRGAMGFILMYDITNEESFNAVQDWATQIKTYSWDNAQVILVGNKCDMEEERVVPTE 148

  Fly   138 TAAEYAAQLGIPFLETSAKSATNVEQAFMTMAAEIKNRVGPPSSATD-----NASKVKIDQGRPV 197
            .....|.|||..|.|.|||...:|.|||..:...|.:::. .|..||     ::...::....|:
Human   149 KGQLLAEQLGFDFFEASAKENISVRQAFERLVDAICDKMS-DSLDTDPSMLGSSKNTRLSDTPPL 212

  Fly   198 ENTKSGC 204
            ......|
Human   213 LQQNCSC 219

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab1	NP_732610.1	Rab1_Ypt1	10..175	CDD:206661	83/164 (51%)
RAB3B	NP_002858.2	Rab3	22..186	CDD:206657	82/163 (50%)
		Switch 1. /evidence=ECO:0000269|PubMed:35871249, ECO:0007744|PDB:8A4B	45..58		6/12 (50%)
		Switch 2. /evidence=ECO:0000269|PubMed:35871249, ECO:0007744|PDB:8A4B	78..96		14/17 (82%)