Protein Alignment Rab1 and RAB3A

DIOPT Version :10

• Sequence 1: NP_732610.1
• Gene: Rab1 / 42524
• FlyBaseID: FBgn0285937
• Length: 205
• Species: Drosophila melanogaster
• Sequence 2: NP_002857.1
• Gene: RAB3A / 5864
• HGNCID: 9777
• Length: 220
• Species: Homo sapiens
• Alignment Length: 184
• Identity: 87/184 - (47%)
• Similarity: 125/184 - (67%)
• Gaps: 0/184 - (0%)

  Fly     3 SVNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDT 67
            |.:..:||:||:|:||:|.|||:..|.|:|||::|.:::||:|:|||::||..:.|.||||||||
Human    14 SSDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTIYRNDKRIKLQIWDT 78

  Fly    68 AGQERFRTITSSYYRGAHGIIVVYDCTDQESFNNVKQWLEEIERYACENVNKLLVGNKSDLTTKK 132
            |||||:||||::|||||.|.|::||.|::||||.|:.|..:|:.|:.:|...||||||.|:..::
Human    79 AGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYSWDNAQVLLVGNKCDMEDER 143

  Fly   133 VVDHTTAAEYAAQLGIPFLETSAKSATNVEQAFMTMAAEIKNRVGPPSSATDNA 186
            ||......:.|..||..|.|.|||...||:|.|..:...|..::.......|.|
Human   144 VVSSERGRQLADHLGFEFFEASAKDNINVKQTFERLVDVICEKMSESLDTADPA 197

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab1	NP_732610.1	Rab1_Ypt1	10..175	CDD:206661	83/164 (51%)
RAB3A	NP_002857.1	Rab3	22..186	CDD:206657	82/163 (50%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P63012	49..58		3/8 (38%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P63012	80..96		12/15 (80%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	194..220		2/4 (50%)