Protein Alignment Rab1 and RAB25

DIOPT Version :10

• Sequence 1: NP_732610.1
• Gene: Rab1 / 42524
• FlyBaseID: FBgn0285937
• Length: 205
• Species: Drosophila melanogaster
• Sequence 2: NP_065120.2
• Gene: RAB25 / 57111
• HGNCID: 18238
• Length: 213
• Species: Homo sapiens
• Alignment Length: 203
• Identity: 87/203 - (42%)
• Similarity: 126/203 - (62%)
• Gaps: 4/203 - (1%)

  Fly     7 EYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQE 71
            :|:::||::|||:|||||:.||.||..:.::....:||||:|..||:.|....:|.|||||||.|
Human     8 DYNFVFKVVLIGESGVGKTNLLSRFTRNEFSHDSRTTIGVEFSTRTVMLGTAAVKAQIWDTAGLE 72

  Fly    72 RFRTITSSYYRGAHGIIVVYDCTDQESFNNVKQWLEEIERYACENVNKLLVGNKSDLTTKKVVDH 136
            |:|.|||:|||||.|.::|:|.|..:::..|::||:|:..:|...:..:||||||||:..:.|..
Human    73 RYRAITSAYYRGAVGALLVFDLTKHQTYAVVERWLKELYDHAEATIVVMLVGNKSDLSQAREVPT 137

  Fly   137 TTAAEYAAQLGIPFLETSAKSATNVEQAFMTMAAEIKNRVGP--PSSATDNASKVKIDQG--RPV 197
            ..|..:|...|:.||||||..:||||.||.|:..||..:|..  .:|...||..:...|.  .|.
Human   138 EEARMFAENNGLLFLETSALDSTNVELAFETVLKEIFAKVSKQRQNSIRTNAITLGSAQAGQEPG 202

  Fly   198 ENTKSGCC 205
            ...|..||
Human   203 PGEKRACC 210

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab1	NP_732610.1	Rab1_Ypt1	10..175	CDD:206661	77/164 (47%)
RAB25	NP_065120.2	Rab11_like	11..174	CDD:206660	76/162 (47%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P62820	35..49		4/13 (31%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P62820	67..84		12/16 (75%)