DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Rab1 and Rab19

DIOPT Version :9

Sequence 1:	NP_732610.1	Gene:	Rab1 / 42524	FlyBaseID:	FBgn0285937	Length:	205	Species:	Drosophila melanogaster
Sequence 2:	NP_001019497.1	Gene:	Rab19 / 500088	RGDID:	1565263	Length:	217	Species:	Rattus norvegicus

Alignment Length:	173	Identity:	88/173 - (50%)
Similarity:	121/173 - (69%)	Gaps:	5/173 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 SVNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDT 67
            :|:...|||||::|||||.|||:|::..|....|:||..:||||||.:|::|:|||.:|:|:|||
  Rat     9 TVDENVDYLFKVILIGDSNVGKTCVVQHFKSGVYSESQQNTIGVDFTVRSLEIDGKKVKMQVWDT 73

  Fly    68 AGQERFRTITSSYYRGAHGIIVVYDCTDQESFNNVKQWLEEIERYACENVNKLLVGNKSDLTTKK 132
            ||||||||||.||||.||..|:.||.|.:.:|.:|..|:.|||:|...|:..:|:||||||..|:
  Rat    74 AGQERFRTITQSYYRSAHAAIIAYDLTRRSTFESVPHWIHEIEKYGAANLVIMLIGNKSDLWEKR 138

  Fly   133 VV---DHTTAAEYAAQLGIPFLETSAKSATNVEQAFMTMAAEI 172
            .|   |..|.||....|.:  ||||||.:.|:::.|:.||.|:
  Rat   139 HVLFEDACTLAEKYGLLAV--LETSAKESRNIDEVFVLMAKEL 179

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab1	NP_732610.1	Rab1_Ypt1	10..175	CDD:206661	86/166 (52%)
Rab19	NP_001019497.1	Rab19	15..179	CDD:133267	86/165 (52%)
Rab19	NP_001019497.1	Effector region. /evidence=ECO:0000250	46..54		4/7 (57%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0084
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1149105at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820