DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab1 and rab13

DIOPT Version :9

Sequence 1:	NP_732610.1	Gene:	Rab1 / 42524	FlyBaseID:	FBgn0285937	Length:	205	Species:	Drosophila melanogaster
Sequence 2:	NP_958486.1	Gene:	rab13 / 373105	ZFINID:	ZDB-GENE-030826-30	Length:	200	Species:	Danio rerio

Alignment Length:	193	Identity:	100/193 - (51%)
Similarity:	145/193 - (75%)	Gaps:	9/193 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 EYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQE 71
            :||:||||||||||||||:||::|||:|.:..:||||||:|||::|||::||.:|||:|||||||
Zfish     4 KYDFLFKLLLIGDSGVGKTCLIIRFAEDNFNSTYISTIGIDFKVKTIEVEGKKVKLQVWDTAGQE 68

  Fly    72 RFRTITSSYYRGAHGIIVVYDCTDQESFNNVKQWLEEIERYACENVNKLLVGNKSDLTTKKVVDH 136
            ||:|||::|||||.|||:|||.||::|:.|::.|::.|:..|...|:::|:|||.|:..|:.|..
Zfish    69 RFKTITTAYYRGAMGIILVYDITDEKSYENIQNWMKSIKENASAGVSRMLLGNKCDIEAKRKVSK 133

  Fly   137 TTAAEYAAQLGIPFLETSAKSATNVEQAFMTMAAEI---KNRVGPPS------SATDNASKVK 190
            .|..:.|.:.||.|.||||||:.|||::|.::|.:|   .|:...||      ::|:..|..|
Zfish   134 ETGEKLAKEHGIRFFETSAKSSINVEESFTSLARDILLKSNKKPGPSGREVKLTSTEKKSSSK 196

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab1	NP_732610.1	Rab1_Ypt1	10..175	CDD:206661	92/167 (55%)
rab13	NP_958486.1	Rab8_Rab10_Rab13_like	6..172	CDD:206659	93/165 (56%)
		RAB	9..170	CDD:197555	90/160 (56%)
		Effector region. /evidence=ECO:0000250	37..45		6/7 (86%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	173..195		5/21 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910