Protein Alignment Rab1 and RAB30

DIOPT Version :10

• Sequence 1: NP_732610.1
• Gene: Rab1 / 42524
• FlyBaseID: FBgn0285937
• Length: 205
• Species: Drosophila melanogaster
• Sequence 2: NP_055303.2
• Gene: RAB30 / 27314
• HGNCID: 9770
• Length: 203
• Species: Homo sapiens
• Alignment Length: 199
• Identity: 88/199 - (44%)
• Similarity: 131/199 - (65%)
• Gaps: 3/199 - (1%)

  Fly     7 EYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQE 71
            :||:|||::|||::||||:||:.||....:.....:||||||.|:|:|::|:.:|||||||||||
Human     5 DYDFLFKIVLIGNAGVGKTCLVRRFTQGLFPPGQGATIGVDFMIKTVEINGEKVKLQIWDTAGQE 69

  Fly    72 RFRTITSSYYRGAHGIIVVYDCTDQESFNNVKQWLEEIERYACENVNKLLVGNKSDLTTKKVVDH 136
            |||:||.||||.|:.:|:.||.|.:|||..:.:||.|||:||...|..:|||||.||..::.|..
Human    70 RFRSITQSYYRSANALILTYDITCEESFRCLPEWLREIEQYASNKVITVLVGNKIDLAERREVSQ 134

  Fly   137 TTAAEYAAQLGIPFLETSAKSATNVEQAFMTMAAEIKNRVGPPSSATDNASKVKIDQGRPVENTK 201
            ..|.|::....:.:||||||.:.|||:.|:.:|..:.:. ...::..:|.|.....:|:.:....
Human   135 QRAEEFSEAQDMYYLETSAKESDNVEKLFLDLACRLISE-ARQNTLVNNVSSPLPGEGKSISYLT 198

  Fly   202 SGCC 205
              ||
Human   199 --CC 200

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab1	NP_732610.1	Rab1_Ypt1	10..175	CDD:206661	81/164 (49%)
RAB30	NP_055303.2	Rab30	3..171	CDD:133314	83/165 (50%)
		Switch-I. /evidence=ECO:0000255|PROSITE-ProRule:PRU00753	36..44		2/7 (29%)
		Switch-II. /evidence=ECO:0000255|PROSITE-ProRule:PRU00753	67..83		12/15 (80%)