Protein Alignment Rab1 and Rab5b

DIOPT Version :10

• Sequence 1: NP_732610.1
• Gene: Rab1 / 42524
• FlyBaseID: FBgn0285937
• Length: 205
• Species: Drosophila melanogaster
• Sequence 2: NP_803130.1
• Gene: Rab5b / 19344
• MGIID: 105938
• Length: 215
• Species: Mus musculus
• Alignment Length: 199
• Identity: 83/199 - (41%)
• Similarity: 120/199 - (60%)
• Gaps: 11/199 - (5%)

  Fly    12 FKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTI 76
            |||:|:|:|.||||.|:|||....:.|...||||..|..:::.||..|:|.:|||||||||:.::
Mouse    21 FKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQSVCLDDTTVKFEIWDTAGQERYHSL 85

  Fly    77 TSSYYRGAHGIIVVYDCTDQESFNNVKQWLEEIERYACENVNKLLVGNKSDLTTKKVVDHTTAAE 141
            ...|||||...|||||.|:||:|...|.|::|::|.|..::...|.|||:||..|::|::..|..
Mouse    86 APMYYRGAQAAIVVYDITNQETFARAKTWVKELQRQASPSIVIALAGNKADLANKRMVEYEEAQA 150

  Fly   142 YAAQLGIPFLETSAKSATNVEQAFMTMAAEIKNRVGPPSSATDN----ASKVK-IDQGRPVENTK 201
            ||....:.|:|||||:|.||...|:.:|.::      |.|...|    |.:.: :|.....:..|
Mouse   151 YADDNSLLFMETSAKTAMNVNDLFLAIAKKL------PKSEPQNLGGAAGRSRGVDLHEQSQQNK 209

  Fly   202 SGCC 205
            |.||
Mouse   210 SQCC 213

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab1	NP_732610.1	Rab1_Ypt1	10..175	CDD:206661	74/162 (46%)
Rab5b	NP_803130.1	Rab5_related	20..182	CDD:206653	74/166 (45%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P20339	44..56		5/11 (45%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P20339	77..93		8/15 (53%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	186..215		7/28 (25%)