DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab1 and Rab3c

DIOPT Version :9

Sequence 1:	NP_732610.1	Gene:	Rab1 / 42524	FlyBaseID:	FBgn0285937	Length:	205	Species:	Drosophila melanogaster
Sequence 2:	NP_598220.1	Gene:	Rab3c / 171058	RGDID:	620923	Length:	227	Species:	Rattus norvegicus

Alignment Length:	207	Identity:	92/207 - (44%)
Similarity:	134/207 - (64%)	Gaps:	6/207 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 SVNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDT 67
            |.:..:||:||||:||:|.|||:..|.|:|||::|.:::||:|:|||::|:..:.|.||||||||
  Rat    22 SSDQNFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFKNEKRIKLQIWDT 86

  Fly    68 AGQERFRTITSSYYRGAHGIIVVYDCTDQESFNNVKQWLEEIERYACENVNKLLVGNKSDLTTKK 132
            |||||:||||::|||||.|.|::||.|::||||.|:.|..:|:.|:.:|...:|||||.|:..::
  Rat    87 AGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYSWDNAQVILVGNKCDMEDER 151

  Fly   133 VVDHTTAAEYAAQLGIPFLETSAKSATNVEQAFMTMAAEIKNRVGPPSSATDNA-----SKVKID 192
            ||..........|||..|.|||||...||:|.|..:...|.:::. .|..||.|     ...::.
  Rat   152 VVSTERGRHLGEQLGFEFFETSAKDNINVKQTFERLVDIICDKMS-ESLETDPAITGAKQSTRLK 215

  Fly   193 QGRPVENTKSGC 204
            :..|......||
  Rat   216 ETPPPPQPNCGC 227

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab1	NP_732610.1	Rab1_Ypt1	10..175	CDD:206661	83/164 (51%)
Rab3c	NP_598220.1	Rab3	30..194	CDD:206657	82/163 (50%)
		RAB	31..191	CDD:197555	81/159 (51%)
		Effector region. /evidence=ECO:0000250	59..67		3/7 (43%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	202..227		3/24 (13%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910