Protein Alignment Rab1 and RAB6D

DIOPT Version :10

• Sequence 1: NP_732610.1
• Gene: Rab1 / 42524
• FlyBaseID: FBgn0285937
• Length: 205
• Species: Drosophila melanogaster
• Sequence 2: NP_001071105.1
• Gene: RAB6D / 150786
• HGNCID: 30272
• Length: 254
• Species: Homo sapiens
• Alignment Length: 195
• Identity: 70/195 - (35%)
• Similarity: 111/195 - (56%)
• Gaps: 4/195 - (2%)

  Fly    12 FKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTI 76
            |||:.:|:..|.|:.|:.||..|::..:|.:.||:||..:|:.|:..||.|::||||||||.|::
Human    14 FKLVFLGEQSVAKTSLITRFRYDSFDNTYQAIIGIDFLSKTMYLEDGTIGLRLWDTAGQERLRSL 78

  Fly    77 TSSYYRGAHGIIVVYDCTDQESFNNVKQWLEEIERYACENVNKLLVGNKSDLTTKKVVDHTTAAE 141
            ...|.|.:...:||||.|:..||....:|::::......:|...|||||:||..|:.|.......
Human    79 IPRYIRDSAAAVVVYDITNVNSFQQTTKWIDDVRTEGGSDVIITLVGNKTDLADKRQVSIEEGER 143

  Fly   142 YAAQLGIPFLETSAKSATNVEQAFMTMAAEIKNRVGPPSSATDNASKVKIDQGRPVENTKS--GC 204
            .|..|.:.|:||.||:..||:|.|..:||.:.........:.::.|.:|::  :|.|.|.|  ||
Human   144 KAKGLNVTFIETRAKAGYNVKQLFRRVAAALPGMESTQDGSREDMSDIKLE--KPQEQTVSEGGC 206

  Fly   205  204
            Human   207  206

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab1	NP_732610.1	Rab1_Ypt1	10..175	CDD:206661	62/162 (38%)
RAB6D	NP_001071105.1	Rab6	14..174	CDD:206654	62/159 (39%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P20340	32..50		6/17 (35%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P20340	69..88		9/18 (50%)