Protein Alignment Rab1 and RAB40A

DIOPT Version :10

• Sequence 1: NP_732610.1
• Gene: Rab1 / 42524
• FlyBaseID: FBgn0285937
• Length: 205
• Species: Drosophila melanogaster
• Sequence 2: NP_543155.2
• Gene: RAB40A / 142684
• HGNCID: 18283
• Length: 277
• Species: Homo sapiens
• Alignment Length: 183
• Identity: 75/183 - (40%)
• Similarity: 107/183 - (58%)
• Gaps: 6/183 - (3%)

  Fly     3 SVNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDT 67
            |.:..||:|.|.||:||..||||.:|....|......|....|:|:|..||.|||:.:||::|||
Human     6 SPDQAYDFLLKFLLVGDRDVGKSEILESLQDGAAESPYSHLGGIDYKTTTILLDGQRVKLKLWDT 70

  Fly    68 AGQERFRTITSSYYRGAHGIIVVYDCTDQESFNNVKQWLEEIERYACENVNKLLVGNKSDLTTKK 132
            :||.||.||..||.|||.|:|:|||..::.||..:.:|:::||.:| ..|.|:||||:..|..|:
Human    71 SGQGRFCTIFRSYSRGAQGVILVYDIANRWSFEGMDRWIKKIEEHA-PGVPKILVGNRLHLAFKR 134

  Fly   133 VVDHTTAAEYAAQLGIPFLETSAKSATNVEQAFMTMAAEI-----KNRVGPPS 180
            .|....|..||.:||:.|.|.|.....|:.::|..:|..:     .|.:|.||
Human   135 QVPREQAQAYAERLGVTFFEVSPLCNFNIIESFTELARIVLLRHRMNWLGRPS 187

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab1	NP_732610.1	Rab1_Ypt1	10..175	CDD:206661	68/169 (40%)
RAB40A	NP_543155.2	P-loop containing Nucleoside Triphosphate Hydrolases	9..277	CDD:476819	74/180 (41%)
		Switch-I. /evidence=ECO:0000255|PROSITE-ProRule:PRU00753	41..49		1/7 (14%)
		Switch-II. /evidence=ECO:0000255|PROSITE-ProRule:PRU00753	72..88		10/15 (67%)
		SOCS_Rab40	187..228	CDD:239711	1/1 (100%)