Protein Alignment Rab1 and RAB31

DIOPT Version :10

• Sequence 1: NP_732610.1
• Gene: Rab1 / 42524
• FlyBaseID: FBgn0285937
• Length: 205
• Species: Drosophila melanogaster
• Sequence 2: NP_006859.2
• Gene: RAB31 / 11031
• HGNCID: 9771
• Length: 195
• Species: Homo sapiens
• Alignment Length: 193
• Identity: 72/193 - (37%)
• Similarity: 110/193 - (56%)
• Gaps: 5/193 - (2%)

  Fly    13 KLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTIT 77
            |:.|:||:|||||.::.||..|.:..:...|||..|..:|:....:..|..||||||||||.::.
Human     8 KVCLLGDTGVGKSSIVCRFVQDHFDHNISPTIGASFMTKTVPCGNELHKFLIWDTAGQERFHSLA 72

  Fly    78 SSYYRGAHGIIVVYDCTDQESFNNVKQWLEEIERYACENVNKLLVGNKSDLTTKKVVDHTTAAEY 142
            ..||||:...::|||.|.|:||..:|:|::|::.:..||:...:.|||.||:..:.|....|.||
Human    73 PMYYRGSAAAVIVYDITKQDSFYTLKKWVKELKEHGPENIVMAIAGNKCDLSDIREVPLKDAKEY 137

  Fly   143 AAQLGIPFLETSAKSATNVEQAFMTMAAEIKNRVGPPSSATDNASKVKIDQGRPVENTKSGCC 205
            |..:|...:|||||:|.|:|:.|..::.:|     ||....:|.:...|...:|.......||
Human   138 AESIGAIVVETSAKNAINIEELFQGISRQI-----PPLDPHENGNNGTIKVEKPTMQASRRCC 195

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab1	NP_732610.1	Rab1_Ypt1	10..175	CDD:206661	65/161 (40%)
RAB31	NP_006859.2	Rab5_related	6..168	CDD:206653	65/164 (40%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P20339	30..42		3/11 (27%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P20339	63..79		9/15 (60%)