Protein Alignment Rab1 and RAB40B

DIOPT Version :10

• Sequence 1: NP_732610.1
• Gene: Rab1 / 42524
• FlyBaseID: FBgn0285937
• Length: 205
• Species: Drosophila melanogaster
• Sequence 2: NP_006813.1
• Gene: RAB40B / 10966
• HGNCID: 18284
• Length: 278
• Species: Homo sapiens
• Alignment Length: 170
• Identity: 73/170 - (42%)
• Similarity: 103/170 - (60%)
• Gaps: 1/170 - (0%)

  Fly     8 YDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQER 72
            ||:|.|.||:|||.|||..:|....|......|....|:|:|..||.|||:.:|||:|||:||.|
Human    11 YDFLLKFLLVGDSDVGKGEILASLQDGAAESPYGHPAGIDYKTTTILLDGRRVKLQLWDTSGQGR 75

  Fly    73 FRTITSSYYRGAHGIIVVYDCTDQESFNNVKQWLEEIERYACENVNKLLVGNKSDLTTKKVVDHT 137
            |.||..||.|||.|:|:|||..::.||:.:.:|::||:.:| ..|.|:||||:..|..|:.|...
Human    76 FCTIFRSYSRGAQGVILVYDIANRWSFDGIDRWIKEIDEHA-PGVPKILVGNRLHLAFKRQVPTE 139

  Fly   138 TAAEYAAQLGIPFLETSAKSATNVEQAFMTMAAEIKNRVG 177
            .|..||.:||:.|.|.|.....|:.::|..:|..:..|.|
Human   140 QAQAYAERLGVTFFEVSPLCNFNITESFTELARIVLLRHG 179

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab1	NP_732610.1	Rab1_Ypt1	10..175	CDD:206661	69/164 (42%)
RAB40B	NP_006813.1	Rab40	9..278	CDD:133321	73/170 (43%)
		Switch-I. /evidence=ECO:0000255|PROSITE-ProRule:PRU00753	41..49		1/7 (14%)
		Switch-II. /evidence=ECO:0000255|PROSITE-ProRule:PRU00753	72..88		10/15 (67%)
		SOCS_Rab40	187..229	CDD:239711
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	242..278