Protein Alignment ETHR and H09F14.1

DIOPT Version :9

• Sequence 1: NP_001287439.1
• Gene: ETHR / 42523
• FlyBaseID: FBgn0038874
• Length: 471
• Species: Drosophila melanogaster
• Sequence 2: NP_001256232.1
• Gene: H09F14.1 / 186709
• WormBaseID: WBGene00010375
• Length: 401
• Species: Caenorhabditis elegans
• Alignment Length: 407
• Identity: 93/407 - (22%)
• Similarity: 168/407 - (41%)
• Gaps: 92/407 - (22%)

  Fly    14 MFFCIVIMLLGVVGNVMVPIVIVKTKDMRNSTNIFLTNLSIADLL----VLLVCTPTVLVEVNTR 74
            |:...:|::.|:.|||:..:.|..::..|.:.||:|..|::||.:    :||:|...
 Worm    12 MYLLPLIVIFGLSGNVISLVTIFHSRLRRVNANIYLIVLTLADSIFLTGILLICFKV-------- 68

  Fly    75 PETWVLGHEMCKAVPFVELTVAHASVLTILAISFERYYAICEPL---KAGYVCTKGRAILICVLA 136
              .|: .:|.|..:.:|.:|.::.|..:..|::.|||.||..||   |.|:|   .||.::
 Worm    69 --DWI-AYEYCVGLEYVLMTASYISSWSTAALTIERYLAIAHPLSHMKYGHV---DRAKVM---- 123

  Fly   137 WGIAALFTSPILWVAE-YKLAEYIDGSSVAVCLTQAISDWTLAFFLMTISVFFVVPFVTLVVLYG 200
                 |:..||.:|.: ::.......:....|..:..:...:|..:.|: :.:|||...:|||..
 Worm   124 -----LYWVPIPFVLQLFQFFSLEPATEERKCALKEANYQIIAQAVDTV-LCYVVPCGIIVVLNI 182

  Fly   201 IIARNLVSNR----AAMLRARPTKPELSLKARKQVVLMLGAVVLSFFVCLLPFRVLTLWIIL--- 258
            ::|..:..::    |...::...:...|..:......:|..:.|.|.|...||.|:.:..|:
 Worm   183 LVALQVQKSQEHFMAETKKSNSRRTGGSSSSSGTWTRILWVMPLVFVVLNTPFYVIMMIEIVFQI 247

  Fly   259 -----STDQTLHDLGLVRYYSLLYFCRIMLYLNSAMNPILYNLMSTKFRR----GFKR-LC---- 309
                 .:..|..:|.:..|.:..|    |.|:|:|::.::|...|..||:    .:|| ||
 Worm   248 IYQSPPSGDTRSELFVTVYNTAHY----MYYMNTAIDVLVYAFSSANFRKTAVIAWKRILCPGYA 308

  Fly   310 --QDAGRLLLELVTLGRRKEDSSRGR---------------------------RGTLSLGMGTNT 345
              |...|.||.:|   ....||.|.|                           |.|:..   .||
 Worm   309 ERQKGKRFLLSMV---HSVSDSIRKRIPIAQPAPHTVLVTDQTSRISYRMTSERSTIRF---PNT 367

  Fly   346 NTNTNSSNATGATSSSI 362
            .:..||...|.:.:.|:
 Worm   368 PSRANSPKLTASNAVSV 384

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ETHR	NP_001287439.1	7tm_4	18..>143	CDD:304433	35/131 (27%)
		7tm_1	27..294	CDD:278431	65/286 (23%)
		7tm_4	<102..307	CDD:304433	49/224 (22%)
H09F14.1	NP_001256232.1	7tm_GPCRs	10..295	CDD:391938	72/310 (23%)
		TM helix 1	10..36	CDD:341315	7/23 (30%)
		TM helix 2	43..67	CDD:341315	9/23 (39%)
		TM helix 3	77..106	CDD:341315	8/28 (29%)
		TM helix 5	158..183	CDD:341315	8/25 (32%)
		TM helix 6	212..242	CDD:341315	7/29 (24%)
		TM helix 7	263..288	CDD:341315	7/28 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910