Protein Alignment ETHR and nmur-3

DIOPT Version :9

• Sequence 1: NP_001287439.1
• Gene: ETHR / 42523
• FlyBaseID: FBgn0038874
• Length: 471
• Species: Drosophila melanogaster
• Sequence 2: NP_001024524.1
• Gene: nmur-3 / 184090
• WormBaseID: WBGene00017176
• Length: 445
• Species: Caenorhabditis elegans
• Alignment Length: 374
• Identity: 94/374 - (25%)
• Similarity: 158/374 - (42%)
• Gaps: 96/374 - (25%)

  Fly    12 TAMFFCIVIMLLGVVGNVMVPIVIVKTKDMRNSTNIFLTNLSIADLLVLLVCTPTVLVEV-NTRP 75
            |.:|  :.:.|:|::||::..|||.||..:.:.||.||.||:.:|..:::|.....||.: |...
 Worm    79 TLIF--VFVGLVGLIGNLLTVIVIFKTNSLHSHTNYFLANLATSDFCLIVVGVSFDLVNIWNDEE 141

  Fly    76 ETWVLGHEMCKAV-PFVELTVAHASVLTILAISFERYYAICEPLKAGYVCTKGRAILICVLAWGI 139
            ...:.|:  |... .|:.| ...||:|||:.::.||:.|||.|.....:..:.|.....:|.|.:
 Worm   142 PLDIFGY--CSLTSTFISL-FTFASILTIVLLTAERFTAICYPFSHRTIFDEKRVKRFILLIWFV 203

  Fly   140 AALFTSPILWVAEY--KLAEYIDG-----SSVAVCLTQAISDWTLAF-FLMTISVFFVVPFVTLV 196
            |.|   |.:::...  ::::...|     :.:..|......|....: |...|::.||:|...::
 Worm   204 ALL---PSIFIGSMFKRVSQDFCGFNRQMTYIGRCDLVTSPDSFFRYPFESAITITFVLPLFFII 265

  Fly   197 VLY----GI------------------IARNLVSNRAAM-------------------------- 213
            ..|    |.                  :..|.:||...:
 Worm   266 YCYFRILGTRHFLCITVNLSYTSNIFPVTLNEMSNSTHVHTPVGTARSDSGAFPFPHTSNNSNTQ 330

  Fly   214 -----LRARPTKPELSLKARKQVVLMLGAVVLSFFVCLLPFRVLTLWIILSTDQTLHDLGLVRYY 273
                 :..:..:|..|.:|:|.|:.||..|...||||.||:....|              :|:|.
 Worm   331 SFPLTVHTKNVQPPRSQQAQKMVIKMLVTVTAVFFVCYLPYHAQRL--------------IVKYN 381

  Fly   274 S----------LLY-FCRIMLYLNSAMNPILYNLMSTKFRRGFKRLCQD 311
            |          ||| ...|:.|:::::|||.|||||.:||.|||:|.:|
 Worm   382 SKDCSNSDFCKLLYPIAGILQYISASLNPIFYNLMSVRFRNGFKKLIKD 430

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ETHR	NP_001287439.1	7tm_4	18..>143	CDD:304433	39/126 (31%)
		7tm_1	27..294	CDD:278431	78/340 (23%)
		7tm_4	<102..307	CDD:304433	62/276 (22%)
nmur-3	NP_001024524.1	7tmA_NTSR-like	76..424	CDD:320110	89/366 (24%)
		TM helix 1	78..102	CDD:320110	9/24 (38%)
		TM helix 2	111..133	CDD:320110	7/21 (33%)
		TM helix 3	150..172	CDD:320110	7/22 (32%)
		TM helix 4	195..211	CDD:320110	5/18 (28%)
		TM helix 5	246..269	CDD:320110	5/22 (23%)
		TM helix 6	351..376	CDD:320110	11/24 (46%)
		TM helix 7	392..417	CDD:320110	11/24 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5416
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940