Protein Alignment ETHR and NMUR1

DIOPT Version :9

• Sequence 1: NP_001287439.1
• Gene: ETHR / 42523
• FlyBaseID: FBgn0038874
• Length: 471
• Species: Drosophila melanogaster
• Sequence 2: NP_006047.3
• Gene: NMUR1 / 10316
• HGNCID: 4518
• Length: 426
• Species: Homo sapiens
• Alignment Length: 332
• Identity: 101/332 - (30%)
• Similarity: 159/332 - (47%)
• Gaps: 61/332 - (18%)

  Fly    18 IVIMLLGVVGNVMVPIVIVKTKDMRNSTNIFLTNLSIADLLVLLVCTPTVLVEV-NTRPETWVLG 81
            ::|.::|.|||.:..:||::.|.||..||.:|.:|:::|||||||..|..|.|: :..|  ::||
Human    68 LLIFVVGAVGNGLTCLVILRHKAMRTPTNYYLFSLAVSDLLVLLVGLPLELYEMWHNYP--FLLG 130

  Fly    82 HEMCKAVPFVELTVAHASVLTILAISFERYYAICEPLKAGYVCTKGRAILICVLAWGIAALFTSP 146
            ...|.....:...|..||||.:.|:|.|||.|:..||:|..:.|:.....:....||:|.|.:.|
Human   131 VGGCYFRTLLFEMVCLASVLNVTALSVERYVAVVHPLQARSMVTRAHVRRVLGAVWGLAMLCSLP 195

  Fly   147 ILWVAEYKLAEYIDGSSV-----------------AVCL---TQAISDWTLAFFLMTISVFFVVP 191
                          .:|:                 |||:   .:|:.:..:.   .|..:||.:|
Human   196 --------------NTSLHGIRQLHVPCRGPVPDSAVCMLVRPRALYNMVVQ---TTALLFFCLP 243

  Fly   192 FVTLVVLYGIIARNLVSNR-----------AAMLRARPT-KPELSLKARKQVVLMLGAVVLSFFV 244
            ...:.|||.:|...|...|           :|..|:|.| :.:...:.|:||..||..:|:.|.:
Human   244 MAIMSVLYLLIGLRLRRERLLLMQEAKGRGSAAARSRYTCRLQQHDRGRRQVTKMLFVLVVVFGI 308

  Fly   245 CLLPFRV-LTLWIILS--TDQTLHDLGLVRYYSLLYFCRIMLYLNSAMNPILYNLMSTKFRRGFK 306
            |..||.. ..:|.::|  || .||    :.:..:.....|..||.||.||:||:|||::||..|:
Human   309 CWAPFHADRVMWSVVSQWTD-GLH----LAFQHVHVISGIFFYLGSAANPVLYSLMSSRFRETFQ 368

  Fly   307 R-LCQDA 312
            . ||..|
Human   369 EALCLGA 375

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ETHR	NP_001287439.1	7tm_4	18..>143	CDD:304433	46/125 (37%)
		7tm_1	27..294	CDD:278431	87/302 (29%)
		7tm_4	<102..307	CDD:304433	65/239 (27%)
NMUR1	NP_006047.3	7tm_1	77..356	CDD:278431	87/302 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5416
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.940