DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5892 and CG11353

DIOPT Version :9

Sequence 1:	NP_650959.2	Gene:	CG5892 / 42522	FlyBaseID:	FBgn0038873	Length:	738	Species:	Drosophila melanogaster
Sequence 2:	NP_647915.1	Gene:	CG11353 / 38560	FlyBaseID:	FBgn0035557	Length:	754	Species:	Drosophila melanogaster

Alignment Length:	797	Identity:	171/797 - (21%)
Similarity:	306/797 - (38%)	Gaps:	182/797 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 VVLILGLAVTSALDFGPEINEGNELDAQDYQR-----LNKVRHLSEQFFSYYKNVTLDDLVP-EG 65
            |:::|||.:.|.|..|.. |:....::..:||     ||....|.::........|::...| |.
  Fly    16 VLMLLGLWLGSVLAKGAS-NQSATTNSHAWQRYHSQALNASPALPDELEILDAPSTIEIHSPHET 79

  Fly    66 RLPTVSDL--------------QCYADFAQLTAGLASGSLWAYRMIDSWGSIPSGILKGHLKDLG 116
            .|...|.:              :|:|...|:..|:.....||.:::|:.|:.|||.:.|....||
  Fly    80 HLTRTSVIFGLTKVANESSVSQKCHAQLRQMQRGILGKQPWAMKVLDASGTKPSGFVYGQNYWLG 144

  Fly   117 HYDECIAIEQSAASGSTLLGK-----------------------YCLASLPLQQLLGNVGRMMN- 157
            ..:.|..:::..  |.||...                       |...:.|.|..:    ::|:
  Fly   145 SREACRGVQRPV--GITLSKNFDRVMHYGIITQQAPFDMDYRVLYLRHNSPWQVEI----KLMSE 203

  Fly   158 --VQTAVCFPASCSATNMDTLLRRVLKQLVGLELNSNQ--------------NLVSENSCKTSER 206
              :...:|.|::||:..:.:|.:   ..:.|.....|:              .|..|...:.|.|
  Fly   204 QIIHIGLCLPSACSSVEVQSLAQ---DYVAGGMFTENEIFDIKPEVVYMKDLQLKDEFFERASFR 265

  Fly   207 DAYDGGAIAAIVILSVFGGAVIISTFYDYFLCADQ----NKLPAI-------------------- 247
                  .:.|.|:|:|           ....||.|    :|:|:|
  Fly   266 ------LLVACVLLTV-----------TLMFCAQQLHATSKMPSISVDPLDRDLAPAESEIWRGL 313

  Fly   248 ----------------------LKVFSARANSRSLFRITTKPNPNVIECLHGLRGMSLIWVCFGH 290
                                  .|:|:.|.|:           .|.|..::|||.:..||:...|
  Fly   314 NSLLQIERLQRYVTCWDVPGNWAKIFAIRENT-----------ANEIPLMNGLRSVCAIWIMVFH 367

  Fly   291 -DFIISMTSPNINLYDVYTWAKTPFKDIIQEGVFAVDSFFFISGLLVAMVALRSMEKAKG----- 349
             .:.:..|..|..:  :.::|:..|...:......||.||.|||.|.....||:..:.:.
  Fly   368 VVWFMYFTVHNKTV--LISYAEQAFFQYVSSAPLLVDVFFTISGFLQTFNFLRNSRQLEAVRQNS 430

  Fly   350 -KLNIPL---MYLHRYLRLTPIVAVSILLYWKLLPHLGDGPLYG-NWNFDSYDRCEGNWYWTLLY 409
             ..|:.|   :..||||||.|:..|.:.....:..::||..:|. |..||  :.|..:|:..||:
  Fly   431 FSENLKLFGKLLFHRYLRLGPLYLVVMATVDLVYAYIGDVSVYHINERFD--EMCTRHWWRNLLF 493

  Fly   410 VQNYATDSE-CLAHTWYLAIDTQLYIIAPILLIIVYKWGKKGAAVVLLLLLGLTAYLFSIIVINN 473
            :||.....: |...:|.||.:.|.:|:|..||.:..|:.|...::|:...:...|:.:.|.:...
  Fly   494 IQNLFDHRDMCANWSWSLACEMQFFILANALLFLYVKYPKVVKSLVVSSFVATIAWSYGIGLSIK 558

  Fly   474 YSL-ISGGGGGGPDDYSEDLDHYTHNRASGWLVGFLFGYFLHTIRGKAIKLSRPAVWIGWITCLA 537
            :.| .......|.:.|:...     .|...:::|.:..:.|...|.: :::|.......|...|.
  Fly   559 FQLSFDAAFATGTEIYTSPF-----VRVLPYILGAVTAWLLQENRVQ-LEISEQKERACWHFALF 617

  Fly   538 FLFTCIFAMYPYGTGKSKTLPTLNEAFYVSLSRIAWPLGLSWVVFACMQGYGGLANSFLTSPLWQ 602
            ..|.||     |.|.|....|.:....:| :.|:.:.|.:.|::.....|.|...:..|.:..:|
  Fly   618 VFFACI-----YSTVKRDLGPLMAITLFV-MGRLFFSLSVCWMIARSCDGRGVWWSRLLEAKGFQ 676

  Fly   603 PLSKLSFCAYMGHLFIQNLNAGRTRVNTYFSNYDIMLRFWQDFGFTVL--LAYVMYIL-IEAPCG 664
            .:|:||:..|:.:..:..|....|..:|:...:.:.:   ...||.|:  ||.:::.| .|.|..
  Fly   677 HVSRLSYAIYLLNPLVIALFYSLTNASTHADPFMLCV---VTCGFAVIVYLASILFSLAFELPFS 738

  Fly   665 GLESLILPNRRPAPQPK 681
            .|.||:  |||.: :||
  Fly   739 NLSSLL--NRRQS-KPK 752

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5892	NP_650959.2	NRF	90..203	CDD:214781	27/152 (18%)
		Acyl_transf_3	272..656	CDD:280013	94/398 (24%)
		OafA	277..685	CDD:224748	104/421 (25%)
CG11353	NP_647915.1	NRF	118..243	CDD:214781	25/133 (19%)
		OafA	349..752	CDD:224748	103/424 (24%)
		Acyl_transf_3	352..729	CDD:280013	93/395 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45453353
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11161
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.950