DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5892 and CG30471

DIOPT Version :9

Sequence 1:	NP_650959.2	Gene:	CG5892 / 42522	FlyBaseID:	FBgn0038873	Length:	738	Species:	Drosophila melanogaster
Sequence 2:	NP_001261001.1	Gene:	CG30471 / 246633	FlyBaseID:	FBgn0050471	Length:	735	Species:	Drosophila melanogaster

Alignment Length:	777	Identity:	173/777 - (22%)
Similarity:	289/777 - (37%)	Gaps:	162/777 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 VSVVVLILGLAV---------------TSALDFGPEI-------NEGNELDAQDYQRLNKVRHLS 46
            :|:.:|::..||               ..:|:..|||       .|...:::.....|.:    |
  Fly    11 ISIWILVVNAAVNESTLRRHRYEYGFLNGSLELSPEIISTDIRGKEAAAIESPHEPHLTR----S 71

  Fly    47 EQFFSYYKNVTLDDLVPEGRLPTVSDLQCYADFAQLTAGLASGSLWAYRMIDSWGSIPSGILKGH 111
            ...|...|.....::.|          .|||...|:..|:.|...||.:::|:.|:.|||.:.|.
  Fly    72 SVIFGLTKVANESNVTP----------SCYAHLKQVQRGILSRQPWAMKVLDASGTKPSGFVFGQ 126

  Fly   112 LKDLGHYDECIAIE---------------------QSAASGSTLLGKYCLASLPLQQLLGNVGRM 155
            ...||..|.|..:.                     |||..|......|.....|.|..:    ::
  Fly   127 NYWLGSRDGCEGVRRPVGITLSRNYERVMHYSILTQSAPFGMDYRVIYMRHRSPWQVEI----KV 187

  Fly   156 MNVQT---AVCFPASCSATNMDTLLR-RVLKQLVGLE--LNSNQNLVSENSCKTSERDAYDGGAI 214
            |:.|.   .:|.|:|||:..:..|.| .|...|...:  .:....::.....:.||| .|.....
  Fly   188 MSEQVLHIGLCLPSSCSSEEVKQLARYYVAGDLFAADDMFDMKPEVLYMKDLRLSER-FYQRLTF 251

  Fly   215 AAIVILSVFGGAVIISTFYDYFLCADQ----------------------NKLPAILK-------- 249
            ..:|...:..||::        |||.|                      ..|..:||
  Fly   252 RLVVAAILVTGALM--------LCAQQVRVAKRADEPDLGLAPVESELWQALDTLLKWQPFQSFV 308

  Fly   250 -VFSARANSRSLFRITTKPNPNVIECLHGLRGMSLIWVCFGH-DFIISMTSPNINLYDVYTWAKT 312
             .|....|.|.:..: .:..|..|..::|||.:..||:...| .:.:..|..|..:  :.::|:.
  Fly   309 SCFDVANNWRKISAM-RENQPGEIPIMNGLRSVCAIWILIFHVVWYMYFTVHNKTV--LISYAEQ 370

  Fly   313 PFKDIIQEGVFAVDSFFFISGLLVAMVALRSME--------------KAKGKLNIPLMYLHRYLR 363
            .|...:......||.||.|||.|.....||:.:              |..|||     ..|||||
  Fly   371 VFFQYVSTAPLLVDVFFTISGFLQTYNFLRNEQQLDAVRRNGLWGNVKLFGKL-----LFHRYLR 430

  Fly   364 LTPIVAVSILLYWKLLPHLGDGPLYG-NWNFDSYDRCEGNWYWTLLYVQNYATDSE-CLAHTWYL 426
            |.|:..|.:........::||..::. |..||  :.|..:|:..||::||.....| |...:|.|
  Fly   431 LGPLYLVVMGSVDLAFAYIGDVSVFHINERFD--ELCPQHWWRNLLFIQNLFDHREMCANWSWSL 493

  Fly   427 AIDTQLYIIAPILLIIVYKWGKKGAAVVLLLLLGLTAYLFSIIVINNYSLISGGGGGGPDDYSED 491
            |.|.|.:::|.|:|.|..|..|...|:.|..|:|...:.:.|.:...:..      .....|:..
  Fly   494 ACDMQFFLLANIVLFIYAKHEKLAKAITLTGLMGTITWSYGIGIAKKFEF------SFDSTYATG 552

  Fly   492 LDHYTHN--RASGWLVGFLFGYFLHTIRGKAIKLSRPAVWIGWITCLAFLFTCIFAMYPYGTGKS 554
            ...||..  |...::||.:..::....|.:..:||...:...|...|.....||::......|..
  Fly   553 TQIYTSPFVRVLPYIVGAIAAWYYQEQRFQVSELSERRICRWWHFSLKVFVGCIYSTVKRDLGYL 617

  Fly   555 KTLPTLNEAFYVSLSRIAWPLGLSWVVFACMQGYGGLANSFLTSPLWQPLSKLSFCAYMGH---- 615
            .|:     :.:| |.|..:.|.:.|::.....|.|...:..|.:..:|.|::||:..|:.:
  Fly   618 ITI-----SLFV-LGRALFSLTICWMIVGSASGTGVWWSRLLEAKFFQHLNRLSYAIYLLNPLVI 676

  Fly   616 LFIQNLNAGRTRVNTYFSNYDIMLRFWQDFGFT--VLLAYVMYIL-IEAPCGGLESLILPNR 674
            ..:.:|.:..:.|:.:..:....       |||  |.||.:.:.| .|.|...|.||:|..:
  Fly   677 ALVYSLTSTSSAVDPFLLSVICC-------GFTMIVYLASIAFSLAFELPYSNLSSLLLKGK 731

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5892	NP_650959.2	NRF	90..203	CDD:214781	30/139 (22%)
		Acyl_transf_3	272..656	CDD:280013	98/408 (24%)
		OafA	277..685	CDD:224748	104/424 (25%)
CG30471	NP_001261001.1	NRF	105..230	CDD:214781	30/128 (23%)
		OafA	321..719	CDD:224748	101/426 (24%)
		Acyl_transf_3	331..709	CDD:280013	97/405 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45453352
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11161
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.950