DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5892 and oac-53

DIOPT Version :9

Sequence 1:	NP_650959.2	Gene:	CG5892 / 42522	FlyBaseID:	FBgn0038873	Length:	738	Species:	Drosophila melanogaster
Sequence 2:	NP_507205.2	Gene:	oac-53 / 189254	WormBaseID:	WBGene00012308	Length:	704	Species:	Caenorhabditis elegans

Alignment Length:	736	Identity:	200/736 - (27%)
Similarity:	319/736 - (43%)	Gaps:	135/736 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 KVRHLSEQFFSYYKNVTLDDLVPEGRLPT--VSDLQCYADFAQLTAGLASGSLWAYRMIDSWGSI 103
            |:.||:  :....:..|.|..:....|.|  .:..||.|...:........:::|.:.:||:|.:
Worm    26 KIPHLN--YTGVSEQCTKDTKLWLSSLETFVATSTQCMAPGGKCDTKKLEENMFAVQQLDSFGRL 88

  Fly   104 -PSGILKGHLKDL--GHYDECIAIEQSAASGSTLLGKYCL------ASLPLQQLLGNVGRMMNVQ 159
             ..|:|:  |.|.  |:|.||..|     ||......||.      ..||...|        ..:
Worm    89 FEPGLLE--LLDTFEGNYQECERI-----SGIKYDTNYCYMGLIPKIKLPFSSL--------PYR 138

  Fly   160 TAVCFPASCSATNMDTLLRRVLKQLVGLELNSNQNLVSENSCKTSERD-----AYDGGAIAAIVI 219
            :|||.|.||.  ::|  |.::..||       ...|.:....|...:|     |:.|..|...::
Worm   139 SAVCMPRSCQ--HLD--LPKLYNQL-------GSKLFTARFAKCVHQDIEKDSAFWGFTIFMGIM 192

  Fly   220 LSVFGGAVIISTFYDYFLCADQNKLPA---------ILKVFSARANSRSLFRITTKPNPNVIECL 275
            :|:    .|::|..||......| :|:         .|..||...|:..:..: .:..|..|:.|
Worm   193 ISI----AILATSVDYLRETTYN-IPSDKETNLYLKFLLAFSFWTNAGQILSV-KEQKPGFIKSL 251

  Fly   276 HGLRGMSLIWVCFGHDFIISMTSPNINLYDVYTWAKTPFKDIIQEGVFAVDSFFFISGLLVAMVA 340
            ..:|..|:.||..||..:  ....|..|..:....|..:..:......:||:||.:||::||.:.
Worm   252 DCIRAFSISWVIAGHSLL--FFEFNETLIPISNVPKLIWNHLFLNATVSVDTFFLMSGIVVAYLF 314

  Fly   341 LRSMEKA---KGKLNIPLMYLHRYLRLTPIVAVSILLYWKLLPHLGDGPLYGNWNFDSY----DR 398
            .:...|:   |..|...|.||||||||||...:.:..:....|:: .|| |..|.:::.    :.
Worm   315 FKQRPKSSTIKSPLTWILFYLHRYLRLTPPYMIFVGFFVVYGPYI-QGP-YAAWMWNALASMSNY 377

  Fly   399 CEGNWYWTLLYVQNYATDSE--CLAHTWYLAIDTQLYIIAPILLIIVYKWGKKGAAVVLLLLLG- 460
            |..||:..|:|:.|:.|:.:  |...:||||:|||||::|||.|:.:|.....||..::...:|
Worm   378 CRTNWWRNLIYINNFDTNQKTTCYPVSWYLAVDTQLYLVAPIFLVALYFSFAAGAVSIVAGCVGS 442

  Fly   461 -LTAYLFSIIVINNYSLISGGGGGGPDDYSEDLD-HYTHN-------RASGWLVGFLFGYFLHTI 516
             :|.|    |:...|..:|.      |||..|.| |||:.       |.:.:|:|.|.||.:...
Worm   443 IVTTY----ILYGVYDTMSA------DDYHSDPDGHYTNMIYNRPWIRCTPYLLGLLTGYIIANY 497

  Fly   517 RGKAIKLSRPAVWIGWITCLAFLFTCIFAMYPYGTGKSKTLPTLNEAFYVSLSRIAWPLGLSWVV 581
            ..:.|:.:|......|:......|.|:||.|.|..| |...|.:...|. :.||:.|.:.::||:
Worm   498 GKRQIRFNRAISITCWVVAFGIGFACLFANYDYDKG-SYWSPFVKGTFN-NFSRLGWSVAVAWVI 560

  Fly   582 FACMQGYGGLANSFLTSPLWQPLSKLSFCAYMGH---LFIQNLNAGRTRVNTYFSNY-DIMLRF- 641
            .|...|:||..|:|::.|:|||..|||:|||:.|   |:             ||.|. |..|:|
Worm   561 VANHFGWGGPINAFMSHPIWQPFGKLSYCAYIVHWMALY-------------YFLNVGDRPLQFF 612

  Fly   642 --WQDFGF-----TVL---LAYVMYILIEAPCGGLESLIL----------PNRRPAPQP---KVQ 683
              ||.:.:     |:|   .|:....|.|.....||.:::          .:.||.|.|   .:.
Worm   613 NIWQVYCYYAIPATILSYFFAFFWSCLFEVSTLKLEKMLIEAILRIGATTSDSRPKPVPISGGLT 677

  Fly   684 AAEPSKEEIPSPVDLEKQTPE 704
            .||...::.....|:|.:..|
Worm   678 KAEDDLKKTNGSWDIEIEPVE 698

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5892	NP_650959.2	NRF	90..203	CDD:214781	31/121 (26%)
		Acyl_transf_3	272..656	CDD:280013	129/417 (31%)
		OafA	277..685	CDD:224748	135/454 (30%)
oac-53	NP_507205.2	NRF	75..173	CDD:214781	32/123 (26%)
oac-53	NP_507205.2	OafA	242..632	CDD:224748	129/418 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	204	1.000	Domainoid score	I1719
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	238	1.000	Inparanoid score	I2120
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm14368
orthoMCL	1	0.900	-	-		OOG6_100705
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X299
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.870