DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5892 and oac-32

DIOPT Version :9

Sequence 1:	NP_650959.2	Gene:	CG5892 / 42522	FlyBaseID:	FBgn0038873	Length:	738	Species:	Drosophila melanogaster
Sequence 2:	NP_001300114.1	Gene:	oac-32 / 186125	WormBaseID:	WBGene00018708	Length:	707	Species:	Caenorhabditis elegans

Alignment Length:	734	Identity:	192/734 - (26%)
Similarity:	317/734 - (43%)	Gaps:	141/734 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 VSVVVLILGLAVTSALDFGPEINEGNELDAQDYQRLNKVR---HLSEQFFSYYKNVTLDDLVPEG 65
            :.:::|:|.:..|::..: .::.:...||....|.||...   :..|.|.:.|....:.......
Worm     6 IFLIILLLNIIPTTSATW-KDVIKPKPLDNLSAQCLNDTNTWINSLEIFGTLYAECIIMKKCNAK 69

  Fly    66 RLPTVSDLQCYADFAQLTAGLASGSLWAYRMIDSWGSIP-SGILKGHLKDL--GHYDECIAIEQS 127
            .|..:.|                 :|:|.:.:|::|..| :|:|:  ||.|  |.|.||     .
Worm    70 ELKVLRD-----------------NLYAVQQLDAFGQFPGAGLLE--LKTLYDGSYQEC-----Q 110

  Fly   128 AASGSTLLGKYCLASLPLQQLLGNVGR---------------MMNVQTAVCFPASCSATNMDTLL 177
            ..||......||       .||...|:               .:.::.|||.|.||:..:|..:.
Worm   111 RVSGKKYDVNYC-------YLLLTPGKNVSSCAPSNSKSLYSQLPLRIAVCLPDSCNHQDMIDIF 168

  Fly   178 RRVLKQLVGLELNSNQNLVSENSCKTSE--RDA-YDGGAIAAIVILSVFGGAVII----STFYDY 235
            .         ||:..........|..:|  :|. :.|.:|..||::.:...|.|:    .|.|..
Worm   169 N---------ELSPYPFTACSAYCTKNEVKKDTPFWGFSIFLIVMVVIAAIASIVDYVRETVYGL 224

  Fly   236 FLCADQNKLPAILKVFSARANSRSLFRITTKPNPNVIECLHGLRGMSLIWVCFGHDF---IISMT 297
            ....:.|....||..||...|:..|..:..:.: ..|:.|..:|.:|:.||..||.|   |::.|
Worm   225 SSQKENNTFFKILLTFSLWTNAELLLSVKEQKS-GFIKSLDCIRLLSMCWVVTGHSFLYLILADT 288

  Fly   298 SPNINLYDVYTWAKTPFKDIIQEGVFAVDSFFFISGLLVAMVALRSMEKAKGKLNIP----LMYL 358
            ...:..:..|.|     ..::.....:||:||.:||::||.:..:: :..|..:..|    |.|:
Worm   289 LEPVLDFPTYFW-----NHLLLNAFVSVDTFFVLSGIVVAYLFFKT-KLTKKTITSPMTWILFYV 347

  Fly   359 HRYLRLTPIVAVSILLYWKLLPHLGDGPLYGNWNFDSYDR-------CEGNWYWTLLYVQNY--- 413
            ||||||||.|.:.|..:....|:     :.|.::....::       |:..|:..|||:.|:
Worm   348 HRYLRLTPPVMLFIGFFTVYTPY-----IQGAFSASELNQMAPQAAACKTLWWQNLLYINNFDDG 407

  Fly   414 -ATDSECLAHTWYLAIDTQLYIIAPILLIIVYKWGKKGAAVVLLLLLG--LTAY-LFSIIVINNY 474
             :.:|.|...|||||:|||||::|||:|:.:|.....|.|:::...:|  :|.| ||.:     |
Worm   408 NSQNSTCYGITWYLAVDTQLYLVAPIVLVALYFSFAAGTAIIVAGCVGSIITTYILFGV-----Y 467

  Fly   475 SLISGGGGGGPDD------YSEDLDHYTHNRASGWLVGFLFGYFLHTIRGKAIKLSRPAVWIGWI 533
            ::.:...|.|...      ||:     ...|...:|||.|.||.|.|...:.|:|:......|||
Worm   468 NVPADIIGNGDQTKFFNIAYSK-----PWIRCPPYLVGLLTGYLLATYGSRKIRLNWALAIAGWI 527

  Fly   534 TCLAFLFTCIFAMYPYGTGKSKTLPTLNEAFYVSLSRIAWPLGLSWVVFACMQGYGGLANSFLTS 598
            |.......|:||.|.|..|...:  |...|.:.:..|:.|.:.:.|||.|...|:||..:.|::.
Worm   528 TAFVIAGFCLFATYDYDKGAHWS--TFTRATFYNFHRLGWGVFVCWVVGANHMGWGGPIDKFMSH 590

  Fly   599 PLWQPLSKLSFCAYMGHLFIQNLNAGRTRVNTYFSNYDIMLRF---WQDFGF----TVLLAYVMY 656
            |:|||..:||:|||:.|..          |..|:.|...:|.:   ||.|.:    ..||:||:.
Worm   591 PIWQPFGRLSYCAYIVHWM----------VLYYYLNVGGVLHYSSAWQVFTYIAIPATLLSYVLA 645

  Fly   657 I----LIEAPCGGLESLIL 671
            .    |.|.|...||.:::
Worm   646 FFWSCLFEVPILKLEKMLI 664

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5892	NP_650959.2	NRF	90..203	CDD:214781	31/130 (24%)
		Acyl_transf_3	272..656	CDD:280013	126/417 (30%)
		OafA	277..685	CDD:224748	129/433 (30%)
oac-32	NP_001300114.1	NRF	77..185	CDD:214781	31/130 (24%)
oac-32	NP_001300114.1	OafA	254..659	CDD:224748	129/438 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	204	1.000	Domainoid score	I1719
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	238	1.000	Inparanoid score	I2120
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm14368
orthoMCL	1	0.900	-	-		OOG6_100705
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X299
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.870