DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5892 and oac-3

DIOPT Version :9

Sequence 1:	NP_650959.2	Gene:	CG5892 / 42522	FlyBaseID:	FBgn0038873	Length:	738	Species:	Drosophila melanogaster
Sequence 2:	NP_506446.2	Gene:	oac-3 / 182290	WormBaseID:	WBGene00007361	Length:	691	Species:	Caenorhabditis elegans

Alignment Length:	730	Identity:	201/730 - (27%)
Similarity:	318/730 - (43%)	Gaps:	152/730 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 DYQRLNKVRHLSEQFFSYYKNVTLDDLVPEGRLPTVSDLQCY-ADFAQLTA-------------- 84
            ||.::......|.  |..|.:||     ||    ...|::.: :...|.||
Worm    24 DYGKIESFEPFSS--FINYSHVT-----PE----CTKDMKTWISSIEQFTAASSDCLFFKNCTAS 77

  Fly    85 --GLASGSLWAYRMIDSWGSIPS-GILKGHLKDLGHYDECIAIEQSAASGSTLLGKYCLASL-PL 145
              .:...:::|.:..|::..||| |:|:..|...|.|.||..|     ||......||...| |.
Worm    78 ILNILKDNIYAIQQYDAFAKIPSAGLLEVSLVFDGSYQECHRI-----SGVKYETNYCYVLLVPG 137

  Fly   146 QQL------LGNVGRMMNVQTAVCFPASCSATNMDTLLRRVLKQLVGLELNSNQNLVSENSCKT- 203
            :..      :.|.|..:..:.|||.|.||:::  ||:  .:..||..|.|         .:|.|
Worm   138 RNANCSGGSIQNAGTSVAFRRAVCMPKSCASS--DTV--DLYNQLSALPL---------TACATF 189

  Fly   204 -SERD-----AYDGGAIAAIVILSVFGGAVIISTFYDYF----------LCADQNKLPAILKVFS 252
             |:||     |:.|.:....||:|    .||::|..||.          .......|..:|..||
Worm   190 CSQRDVPKDSAFWGFSAFMFVIVS----TVILATTVDYLRESVYDISSKSIEKSASLYRLLYSFS 250

  Fly   253 ARANSRSLFRITTKPNPNVIECLHGLRGMSLIWVCFGHDFIISMTSPNINLYDVYTWAKT--PFK 315
            ...|:.::..::::|..: |:||..:||:|:.||..||            :.:.:.:|.|  |.|
Worm   251 FWTNASTILNVSSQPATH-IKCLDCIRGLSMAWVLSGH------------MLNYFAFADTLMPIK 302

  Fly   316 D--------IIQEGVFAVDSFFFISGLLVAMVALRSMEKAKGKLNIP----LMYLHRYLRLTPIV 368
            .        .....||:||:||.:||:.||....|.....| .|..|    |.|:|||:||||..
Worm   303 SFANYFADYFFMNAVFSVDTFFLVSGITVAYSFFRLKPTTK-TLKSPATWILFYVHRYVRLTPPY 366

  Fly   369 AVSILLYWKLLPHLGDGPLYGN-WNFD--SYDRCEGNWYWTLLYVQNYAT-DSECLAHTWYLAID 429
            .:.|..|.....:: .|||..: :||.  ..:.|:.:|:..|:|:.|:.. ::.|...:||||:|
Worm   367 IIFIGFYAVYALYI-QGPLAASLFNFTVLQVEACKASWWRNLIYINNFDNGENPCYGPSWYLAVD 430

  Fly   430 TQLYIIAPILLIIVYKWGKKGAAVVLLLLLGLTAYLFSIIVINNYSLISGGGGGGPDDYSED--- 491
            ||||::|||||:.:......|..|.::..:|....:|  |:...:.:.:       |.::.|
Worm   431 TQLYLVAPILLVALTWTPIAGLVVSMVGCIGSMIIVF--ILYQKFDMPA-------DSFNADSSG 486

  Fly   492 -LDHYTH----NRASGWLVGFLFGYFLHTIRGKAIKLSRPAVWIGWITCLAFLFTCIFAMYPYGT 551
             .:.|.:    .|...:|||.|.||||.......:|||.....|..:..:..:|.|:.|...|..
Worm   487 KFNFYVYQKPWTRCPPYLVGILGGYFLSRFATSPVKLSFVKKLIPMLLAVGLIFACLTANIGYDQ 551

  Fly   552 GKSKTLPTLNEAFYVSLSRIAWPLGLSWVVFACMQGYGGLANSFLTSPLWQPLSKLSFCAYMGHL 616
            |...:  :..:|.|.:.||..|.|.:.|::.:|..|:.|...:|::.|:||||.:||:.||:.||
Worm   552 GDHWS--SWTKATYYNFSRFFWALSVLWIILSCHYGWAGPIGNFMSHPIWQPLGRLSYSAYIVHL 614

  Fly   617 FIQNLNAGRTRVNTYFSNY-DIMLRF---WQDFGFTVLLAYVM-YI-------LIEAPCGGLESL 669
            .          |..||.|. |..|.|   ||.:.:.:|.|.:: ||       |.|.|...||..
Worm   615 M----------VVYYFLNVGDKPLHFVSTWQVYVYYILPATILTYIFAFFWSCLFEIPVVKLEKF 669

  Fly   670 ---ILPNRRPAPQPK 681
               ||..::..|:.|
Worm   670 LLEILLRKKRLPEKK 684

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5892	NP_650959.2	NRF	90..203	CDD:214781	34/120 (28%)
		Acyl_transf_3	272..656	CDD:280013	123/414 (30%)
		OafA	277..685	CDD:224748	131/446 (29%)
oac-3	NP_506446.2	NRF	85..191	CDD:214781	35/123 (28%)
oac-3	NP_506446.2	Acyl_transf_3	269..653	CDD:376607	125/418 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	204	1.000	Domainoid score	I1719
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	238	1.000	Inparanoid score	I2120
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm14368
orthoMCL	1	0.900	-	-		OOG6_100705
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X299
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.870