DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5892 and oac-7

DIOPT Version :9

Sequence 1:	NP_650959.2	Gene:	CG5892 / 42522	FlyBaseID:	FBgn0038873	Length:	738	Species:	Drosophila melanogaster
Sequence 2:	NP_507120.3	Gene:	oac-7 / 180096	WormBaseID:	WBGene00007835	Length:	702	Species:	Caenorhabditis elegans

Alignment Length:	724	Identity:	196/724 - (27%)
Similarity:	321/724 - (44%)	Gaps:	117/724 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 NEGNELDAQDYQRLNKVRHLSEQFFSYYKNVTLDDLVPEGRLPTVSDLQCYADFAQLTAGLASGS 90
            |..|.|:..:.|..|..|... |.......|::|.|:  .|.....::|...|           :
Worm    33 NASNSLNEVNAQCANDTRTWL-QSLKLVAEVSVDCLI--SRKCNKKEIQIIKD-----------N 83

  Fly    91 LWAYRMIDSWGSIP-SGILKGHLKDLGHYDECIAIEQSAASGSTLLGKYC-LASLPLQQ---LLG 150
            .:|...:|::|.:| |||.:..|...|.|.||..|     ||......|| |..:|.:.   .:|
Worm    84 FYAIEQLDAFGKLPSSGIFEVPLIFDGSYQECQRI-----SGKKYETNYCYLVLVPGRNSSCSIG 143

  Fly   151 NVGRMMN----VQTAVCFPASCSATNMDTLLRRVLKQLVGLELNSNQNLVSENSCKT------SE 205
            ..|..:.    .::|.|...||::.::..|..::             .|:...:|..      .|
Worm   144 GGGGFLPSAAFFRSATCMSVSCTSEDLPQLFNQL-------------PLMPFTACAAFCSSFPVE 195

  Fly   206 RD-AYDGGAIAAIVILSVFGGAVIISTFYDYFLCADQNK---------LPAILKVFSARANSRSL 260
            :| |:.|.:....|::|:    ::::||.||...|.:|:         :..:|..||...|:..|
Worm   196 KDSAFWGFSAFMCVMISI----LVLATFIDYLKDAMKNEHSPPPQPNLIMKMLLTFSLWTNAGVL 256

  Fly   261 FRITTKPNPNVIECLHGLRGMSLIWVCFGHDFIISMTSPNINLYDVYTWAKTPFKDIIQEGVFAV 325
            ..: .:..|..|:||..:|.:|::||..||.|  :...|...|..:..:....:..::.....:|
Worm   257 LSV-KEQKPGFIKCLDCIRFLSMLWVVTGHTF--TFVIPPDTLLSMSHFTDHFWNHLLLNAFVSV 318

  Fly   326 DSFFFISGLLVAMVALRSMEKA---KGKLNIPLMYLHRYLRLTPIVAVSI---LLYWKLLPHLGD 384
            |:||.:||::||.:..:...|:   |..|...:.|:||||||||...:.|   ::|.|.:    .
Worm   319 DTFFLLSGIVVAYLFFKQKHKSSQIKSPLTWIIFYMHRYLRLTPPYMIFIGFYIVYGKYV----Q 379

  Fly   385 GPLYG---NWNFDSYDRCEGNWYWTLLYVQNYATDS-ECLAHTWYLAIDTQLYIIAPILLIIVYK 445
            ||...   |....|...||..|:..|.|:.|....| .|.|.:||||:||||||.|||:|:.:|.
Worm   380 GPFSASQFNTLLSSIATCESYWWKNLFYINNMGDSSTACYAPSWYLAVDTQLYIFAPIILVGLYY 444

  Fly   446 WGKKGAAVVLLLLLG--LTAY-LFSIIVINNYSLISGGGGGGPDDYSED-LDHYTHNRASGWLVG 506
            ....|::::.:.::|  :|.| |:||     |.|.:...|.|..:...| :.|....|...:|:|
Worm   445 SAIIGSSLIAVGMIGSLVTVYILYSI-----YDLPADFFGNGNTNLLYDMIYHKPWIRCPPYLIG 504

  Fly   507 FLFGYFLHTIRGKAIKLSRPAVWIGWITCLAFLFTCIFAMYPYGTGKSKTLPTLNEAFYVSLSRI 571
            .|.||.|.....:.|::......|||:........|:|:.|.|..|...::  ...|.|.:.|||
Worm   505 LLIGYGLAVFGQRKIRIHWFLAVIGWLVAFGLGMACMFSTYDYDKGAYWSI--FARATYYNFSRI 567

  Fly   572 AWPLGLSWVVFACMQGYGGLANSFLTSPLWQPLSKLSFCAYMGHLFIQNLNAGRTRVNTYFSNYD 636
            ||.:.:|||:.|...|:||..::|::.|:||||.:||:|||:.|.|         .:..|.:..|
Worm   568 AWSIAVSWVIVANHMGWGGPIDAFMSHPMWQPLGRLSYCAYIVHFF---------TLFWYLNIND 623

  Fly   637 IMLRFWQDFGFTV-------LLAYVMYI----LIEAPCGGL-----ESLILPNRR---PAPQPKV 682
            ..:.|:..|...:       ||:|:...    |.|.|...|     |:::..|:|   ...:..|
Worm   624 SSMHFYSTFQVFIYYAVPACLLSYIFAFFWSSLFEIPILKLKKMMIEAILQRNQRSELTQVETLV 688

  Fly   683 QAAEPSKEE 691
            |.:....||
Worm   689 QESNAGSEE 697

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5892	NP_650959.2	NRF	90..203	CDD:214781	28/121 (23%)
		Acyl_transf_3	272..656	CDD:280013	126/404 (31%)
		OafA	277..685	CDD:224748	132/440 (30%)
oac-7	NP_507120.3	NRF	83..191	CDD:214781	28/125 (22%)
oac-7	NP_507120.3	OafA	261..666	CDD:224748	131/426 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	204	1.000	Domainoid score	I1719
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	238	1.000	Inparanoid score	I2120
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm14368
orthoMCL	1	0.900	-	-		OOG6_100705
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X299
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.870