DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5892 and oac-55

DIOPT Version :9

Sequence 1:	NP_650959.2	Gene:	CG5892 / 42522	FlyBaseID:	FBgn0038873	Length:	738	Species:	Drosophila melanogaster
Sequence 2:	NP_001317839.1	Gene:	oac-55 / 178792	WormBaseID:	WBGene00021479	Length:	742	Species:	Caenorhabditis elegans

Alignment Length:	795	Identity:	199/795 - (25%)
Similarity:	322/795 - (40%)	Gaps:	167/795 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 VVVLILGLAVTSALDFGPEINEGNELDAQDYQRLNKVRHLSEQFFSYYKNVTLDDLVPEGRLPTV 70
            |.::...|..:|.::|.|  ::..||..:      .:.|..|......|..|.|.:...|.....
Worm    11 VFIIFANLQCSSGIEFDP--HKAMELLGE------LIAHPIEVMEQLEKYKTSDLIAALGIHSNA 67

  Fly    71 S---DLQCYADFAQLTAGLASGSLWAYR---------------------MIDSWGSIPSGILKGH 111
            :   ..:|:.:.:.|..|:...:.:|..                     |:|:.|.:.|||::||
Worm    68 NYSISQECHEELSFLGYGVIDAARYARHHSTAAVPASMTDQERKDYLIPMMDAAGKLGSGIVRGH 132

  Fly   112 LKDLGHYDECIAIEQ-SAASGSTLLGKYCLASLPLQQLL-----GNVGRMMNVQTAVCFPASCSA 170
            :...|.:.||.:|:. |::...|:.|.|..:.:.....:     .:...:..:...:|.|.||..
Worm   133 ILSTGAFSECKSIQMFSSSLNRTVQGDYYSSRILFDMKMRPNSFNSSCNLPQIGVDLCLPWSCRN 197

  Fly   171 TNMDTLLRRVLKQLVGLE-----LNSNQNLVSENSCKTSERDAYDGGAIAAIVILSVFGGAVIIS 230
            .::....|..|.....|.     .|.||.:           .....|....::|||:..|..|:|
Worm   198 EDLTGYFREALGPSKALSPVCSVRNVNQRV-----------PVISLGTWIVLLILSLIVGLCILS 251

  Fly   231 TFYDYFLCADQNKLP--------AILKVFSARANSRSLFRITTKPNPNVIECLHGLRGMSLIWVC 287
            .|.|.|.....|...        .:...||...|.:.:|..........:..|:.:|.:|..||.
Worm   252 GFSDIFQKFQLNDKTRKEEGFGWKLFSAFSFHRNLKEIFNTKNCHKEGQVTSLNCIRVISTFWVI 316

  Fly   288 FGH----DFIISMTSPNINLY----DVYTWAKTPFKDIIQEGVFAVDSFFFISGLLVAMVALRSM 344
            |||    .|:: :|:| |:||    |.||..      :|....|:||:|||||..|::.:..:.:
Worm   317 FGHCSEITFMV-ITNP-IDLYDFTKDTYTGT------LISNAYFSVDTFFFISAFLLSFLWFKQL 373

  Fly   345 EKAKGKLNIP----LMYLHRYLRLTPIVAVSILLYW------------KLLPHLGDGPLYGNWNF 393
            ||....|..|    :.|:||..||:|:..|:||.:.            .:.|.:.|
Worm   374 EKQWNALLSPGGWLMFYVHRIARLSPVYYVTILFFTFVFTRSMVDMPAFMTPAVVD--------- 429

  Fly   394 DSYDRCEGNWYWTLLYVQNYATDSE-CLAHTWYLAIDTQLYIIAPILLIIVYKWGKKGAAVVLLL 457
               |.|:.:::..|||:||.....: |...:||||.|.|:||::|::|:   .:|..||.|.||:
Worm   430 ---DTCQNSYWVNLLYIQNIVGPKDICYFISWYLATDLQIYIMSPLILL---SFGLGGAVVGLLI 488

  Fly   458 LLGLTAYLFSIIVINNYSLI-----SGGGGGGPDD--YSEDLDHYT----HN---RASGWLVGFL 508
               .||...:....|.|.:|     ......||.|  |......|.    ||   |...:::|.:
Worm   489 ---STAAFLASTAFNAYQMIFWHFPPSDYNYGPKDPLYDPSKRRYAAWNYHNPLIRCQIYIMGMV 550

  Fly   509 FGYFLHTIRGKAIKLSRPAV----WIG---WITCLAFLFTCIFAMYPYGTGKSKTLPTLNEAFYV 566
            .|||:..|         |.:    |:.   |...|..:...|..|..|.:|  .....|..|.|.
Worm   551 LGYFMRRI---------PKININPWVDRIMWCLSLGSMIFVIVIMEDYTSG--HLWSPLQTALYS 604

  Fly   567 SLSRIAWPLGLSWVVFACMQGYGGLANSFLTSPLWQPLSKLSFCAYMGHLFIQNLNAGRTRVNTY 631
            ..||:.|.|.|||:|.:... ..||.|.|::.|:|.||::||||||:.||.:.....||.....|
Worm   605 CFSRVVWGLALSWIVISTYY-RKGLINKFMSLPVWTPLARLSFCAYLVHLMVAAYFFGRNHSELY 668

  Fly   632 FSN--YDIMLRFWQDFGFTVLLAYVMYILIEAPCGGLESLIL--PNRRPAPQPKVQAAEPSKEEI 692
            ||.  |.:::........:.|:|.....:.|.|...:|:|:|  .:|..||            :|
Worm   669 FSTLPYFVLVIAIPVISCSFLVAIFWSTMFELPFAKVEALLLGGGSRSSAP------------DI 721

  Fly   693 P-SPVDLEKQTPESS 706
            | :|:|.    ||::
Worm   722 PKTPIDF----PENN 732

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5892	NP_650959.2	NRF	90..203	CDD:214781	27/144 (19%)
		Acyl_transf_3	272..656	CDD:280013	127/431 (29%)
		OafA	277..685	CDD:224748	134/457 (29%)
oac-55	NP_001317839.1	NRF	111..220	CDD:214781	23/108 (21%)
oac-55	NP_001317839.1	OafA	299..690	CDD:224748	125/428 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm14368
orthoMCL	1	0.900	-	-		OOG6_100705
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820