DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5892 and oac-9

DIOPT Version :9

Sequence 1:	NP_650959.2	Gene:	CG5892 / 42522	FlyBaseID:	FBgn0038873	Length:	738	Species:	Drosophila melanogaster
Sequence 2:	NP_491809.2	Gene:	oac-9 / 172323	WormBaseID:	WBGene00016753	Length:	820	Species:	Caenorhabditis elegans

Alignment Length:	782	Identity:	177/782 - (22%)
Similarity:	295/782 - (37%)	Gaps:	209/782 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 EINEGNELDAQDYQRLNKVRHLSEQFFSYYKNVTLDDL-------VPEGRLPTVSDLQCYADFAQ 81
            :|.||   |..::.:.||.:.|       :||...|..       :.:..|..:|  :|
Worm    32 QIFEG---DKDNHTKFNKFQEL-------FKNFEDDSFCINSLGNIGKSALKFLS--EC------ 78

  Fly    82 LTAGLASGSLWAYRMIDSWGSIPSGI-LKGHLKDLGHYDEC---IAIEQSAASGSTLLGKYCLAS 142
             ::.......||.|:|||..:.|.|: .||....:|.::.|   .::|.......||.|...|.|
Worm    79 -SSNTCLEPNWAVRLIDSLPTKPPGLSRKGPFFFIGDFETCKELWSVEHRQVHYCTLKGTVKLGS 142

  Fly   143 --LPLQQLLGNVGRMMNVQTAVCFPASCSATNMDTLLR--------------------------R 179
              ||             |.|.||.|::|....|..||.                          .
Worm   143 ETLP-------------VTTGVCLPSNCHENQMSKLLNLAKEYLFNETIHVDSVYCSHGTDSTWS 194

  Fly   180 VLKQLV-----------------------GLELNSNQNL------------------VSEN---- 199
            |.|..|                       ||...||..:                  :||:
Worm   195 VKKPFVLFSLFFILALLTIGTLTEKMNRDGLIKKSNTKMRRMIHKKSFDVTRSSAVSISEDRSDR 259

  Fly   200 -SCK-TSERDAYDGGAIAAIVILSVFGGAVIISTFYDYFLCADQNKLPAILKVFSARANSRSLFR 262
             ||. .|..::.|..::|...:...|..::.::......:....:.|..||..||.|::...|||
Worm   260 ESCGFDSSGESEDNESLANSSVNRQFAPSIALTYRTLATISLSNSLLVNILSAFSVRSSLTYLFR 324

  Fly   263 ITTKPNPNVIECLHGLRGMSLIWVCFGHDFIISMTSPNINLYD-----------VYTWAKTPFKD 316
            .:|:.    ::.::..|..|..||.|.|..:.|     ::..|           |..|     ::
Worm   325 NSTRD----VKLVNLFRVCSSFWVIFSHTCLFS-----LHFTDTIRSVARKGESVVGW-----RN 375

  Fly   317 IIQEGVFAVDSFFFISGLLVAMVALRSMEKAKGKLN----IPLMYL--HRYLRLTPIVAVSILLY 375
            .:.....|||:|.|:|. .||..::|.....:|..:    |..:.|  ||.|||.|.:::.:|..
Worm   376 FMMNSSLAVDTFLFLSA-CVASYSIRKKILFRGSSSNFSIIKCLALLGHRCLRLLPALSLYLLFM 439

  Fly   376 WKLLPHLGDGPLYGNWNFDSY--DRCEGNWYWT-LLYVQNYATDSECLAHTWYLAIDTQLYIIAP 437
            ..:..||.|||.   ||.:..  ..|.....|. ..:|.|: ..|.|:...||:::|.|||:..|
Worm   440 GLVYNHLADGPF---WNANGMFGTECNVTTIWPHFAFVSNF-FPSTCVPWLWYISLDFQLYLTLP 500

  Fly   438 ILLIIV--YKWGKKGAAVVLLLLLGLTAYLFSIIVI--NNY-SLISGGGGGGPDDYSEDLDH--- 494
            |::..:  :::|...|.|:.:|.|...:.:::|..:  |.: .::||      .....:|..
Worm   501 IVIFFLSKFRFGFTFAIVLCILALVYRSLMYAIYTLPANMFVEMLSG------KFEKAELSFKLL 559

  Fly   495 YTH--NRASGWLVGFLFGYFLHTIR--GKAIKLSRPAVWIGWITCLAF-----LFTCIFAMYPYG 550
            ||.  :|...:.:|.|.|:::..||  |....::...:.|..::.|||     .|...|..||:.
Worm   560 YTSPLSRCPPFFLGILTGWYICQIRYLGTLRSITSFGLKILAVSLLAFALFGPFFYSEFLTYPHA 624

  Fly   551 TGKSKTLPTLNEAFYVSLSRIAWPLGLSWVVFACMQGYG-GLANSFLTSPLWQPLSKLSFCAYMG 614
            ..                :||.|..||:.:|.....||. |:...|....| ..||:|||..|:.
Worm   625 IS----------------NRILWASGLAILVVLAQNGYNFGVFKVFGGQTL-VVLSRLSFGVYLS 672

  Fly   615 H--LFIQNLNAGRTRVNT----YFSNYDIMLRFWQDFGFTVLLAYVMYILIEAPCGGLESLILPN 673
            |  :.:..||:.|..::.    ||....|.:     :..:::.|:.:.|.||.|...||..:|..
Worm   673 HEPILLYYLNSLRQPMSPTSFGYFMFITISI-----YVLSLVCAFFIAISIEVPLLNLERKLLMT 732

  Fly   674 RR 675
            .|
Worm   733 TR 734

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5892	NP_650959.2	NRF	90..203	CDD:214781	40/191 (21%)
		Acyl_transf_3	272..656	CDD:280013	102/427 (24%)
		OafA	277..685	CDD:224748	110/443 (25%)
oac-9	NP_491809.2	NRF	88..187	CDD:214781	29/111 (26%)
oac-9	NP_491809.2	Acyl_transf_3	333..715	CDD:376607	102/424 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11161
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.020