DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5892 and oacyl

DIOPT Version :9

Sequence 1:	NP_650959.2	Gene:	CG5892 / 42522	FlyBaseID:	FBgn0038873	Length:	738	Species:	Drosophila melanogaster
Sequence 2:	XP_021324686.1	Gene:	oacyl / 100002566	ZFINID:	ZDB-GENE-090710-2	Length:	676	Species:	Danio rerio

Alignment Length:	709	Identity:	177/709 - (24%)
Similarity:	293/709 - (41%)	Gaps:	154/709 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 VTLDDL-VPEGRLPTVSDLQCYADFAQLTAGL------ASGSLWAYRMIDSWGSIPSGILKGHLK 113
            |||..| |..|.......|:|..|    |.|.      .:.|.:|..|.|::|.|.|.:..|::.
Zfish     9 VTLMYLFVSNGACARNVSLKCVDD----TMGFLMELQKETPSKFAVIMYDAFGKIGSDVEGGNVN 69

  Fly   114 DLGHYDECIAIEQSAASGSTLLGKYCLASLPLQQLLGNVGRMMNVQTAVCFPASCSATNMDTLL- 177
            ..|...||:::|     |....|:||...|...::...||        ||.|.||:.:.:.||:
Zfish    70 RPGSLRECLSVE-----GPGFRGQYCQVFLKQDKVEYFVG--------VCVPDSCTDSEVQTLVI 121

  Fly   178 -RRVLKQLVGLELNSNQNLVSENS-------CKTSERDAYDGGAIAAIVILSVFGGAVIISTFYD 234
             ....||.:.|..:....|:.:::       |. |:....|   ::|||.|||....:.:.....
Zfish   122 HEAFQKQQMSLLPSVPSILIPDSTLGIFMTQCH-SDSPNID---LSAIVCLSVCCALLALPLIAS 182

  Fly   235 YFLC---------------------------------ADQNK----------------------- 243
            .|:.                                 |:|||
Zfish   183 IFVALIKRKQMREVAPVVGLAQTSNSKQYGTVLTNGSANQNKECSPDLDTTQTKTQNAESKQQSL 247

  Fly   244 ---LPAILKVFSARANSRSLFRITTKPNPNVIECLHGLRGMSLIWVCFGHDFIISMTSPNINLYD 305
               :.:.|:.||.:..|:.|  :.|:.:......|:|:|.:||.|:..||....|..|   :|.:
Zfish   248 SKTVVSWLQGFSVQNCSQGL--LDTEGSGRSYSSLNGIRILSLFWIISGHTVHFSAWS---HLDN 307

  Fly   306 VYTWAKTPFKDIIQEG-----------VFAVDSFFFISGLLVAMVALRSMEKAKGKLNIPLM--Y 357
            ...|     |::::..           ..|||||..:.|||.|...|.::.::...|::.|:  |
Zfish   308 EKRW-----KEMVENNPLYVLTFSGPVYLAVDSFLVLGGLLSAKSLLGTIRRSDNTLSVGLVVNY 367

  Fly   358 L-HRYLRLTPIVAVSILLYWKLLPHLGDGPLYGNWNF--DSYDRCEGNWYWTLLYVQNYATDSE- 418
            | .|:.|:.|:....:.|...|...:..|..   |.|  |....|:..|:..||.:.|..|.::
Zfish   368 LFKRFKRIQPLHLFIVCLVISLFSVVPRGVF---WFFAEDQVLSCKKYWWSNLLLINNLLTITDI 429

  Fly   419 CLAHTWYLAIDTQLYIIAPILLIIVYKWGKKG---AAVVLLLLLGLTAYL---FSIIVINNYSLI 477
            |...||||:||.|.|...| |||.:|:..|..   .:||||:|..:|..|   |..:.::..:.:
Zfish   430 CAPWTWYLSIDFQFYATTP-LLIFLYRMNKCALVVVSVVLLMLSSVTGALITSFLHLPVHQPTTL 493

  Fly   478 SGGGGGGPDDYSEDLDHY---THNRASGWLVGFLFGYFLHTIRGKAIKLSRPAVWIGWITCLAFL 539
            :         |.....:|   .:.|...:|:|.|.|.::.|.:...||....|| |||:..|:.:
Zfish   494 A---------YESYFQYYYNKPYTRYGPYLLGVLAGIYMTTKKEALIKHQWQAV-IGWLCSLSVM 548

  Fly   540 FTCIFAMYPYGTGKSKTLP---TLNEAFYVSLSRIAWPLGLSWVVFACMQGYGGLANSFLTSPLW 601
            ...:...|..     :.:|   ::..|.|..:.|..|.|.|.|::.||.:||||..::||:..||
Zfish   549 ALLVGLAYVL-----RDVPPHLSIPHAIYQGIHRSLWALALIWIILACEEGYGGFVDTFLSLSLW 608

  Fly   602 QPLSKLSFCAYMGHLFIQNLNAGRTRVNTYFSNYDIMLRFWQDFGFTVLLAYVMYILIE 660
            .|||.:||..|:.|..|..|..|:..:..::::::....|......::.:.||:.:|||
Zfish   609 APLSNISFACYLIHPIIIILYNGKQEITMHYTDFNFFYLFLGHLVLSIFIGYVLTVLIE 667

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5892	NP_650959.2	NRF	90..203	CDD:214781	31/121 (26%)
		Acyl_transf_3	272..656	CDD:280013	113/412 (27%)
		OafA	277..685	CDD:224748	115/413 (28%)
oacyl	XP_021324686.1	NRF	48..120	CDD:214781	24/84 (29%)
oacyl	XP_021324686.1	OafA	273..668	CDD:224748	116/422 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170588170
Domainoid	1	1.000	50	1.000	Domainoid score	I11639
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H129774
Inparanoid	1	1.050	178	1.000	Inparanoid score	I4016
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	1	1.000	-	-		FOG0001682
OrthoInspector	1	1.000	-	-		otm25504
orthoMCL	1	0.900	-	-		OOG6_100705
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X299
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	11	10.800