DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment e and AT5G35930

DIOPT Version :9

Sequence 1:	NP_524431.2	Gene:	e / 42521	FlyBaseID:	FBgn0000527	Length:	879	Species:	Drosophila melanogaster
Sequence 2:	NP_001330867.1	Gene:	AT5G35930 / 833582	AraportID:	AT5G35930	Length:	1132	Species:	Arabidopsis thaliana

Alignment Length:	778	Identity:	200/778 - (25%)
Similarity:	325/778 - (41%)	Gaps:	194/778 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 DFVPRALHRIF--EEQQLRHADKVALIYQPSTTGQGMAPSQSSYRQMNERANRAARLLVAETHGR 78
            |.:...||||.  ::.|:..:|   ::|.|.
plant    68 DSLTSRLHRILSNDDSQVAGSD---VVYMPK---------------------------------- 95

  Fly    79 FLQPNSDGDFIVAVCMQPSEGLVTTLLAIWKAGGAYLPIDPSFPANRIHHILLEAKPTLVIRDDD 143
                      :||:.|.||...|.::.::.:.|.|:||:|||:|..|:..::..:..:|||
plant    96 ----------VVALYMPPSVEYVISVFSVLRCGEAFLPLDPSWPRERVLSLISSSNISLVI---- 146

  Fly   144 IDAGRFQGTPTLSTTELYAKSLQLAGSNLLSEE-----MLRGGNDHIAI---------------- 187
                              |..|....|:.|.|.     :|...::.:::
plant   147 ------------------ACGLSSVESHWLVERNVCPVLLFSMDEKLSVETGCSSFVWPCKKERQ 193

  Fly   188 -----VLYTSGSTGVPKGVRLPHESILNRLQWQWATFPYTANEAVSVFKTALTFVDSIAELWGPL 247
                 ::|||||||.||||....:.:|||..|....:|....:..: |||::.|:|.|.|..|.:
plant   194 RKFCYLMYTSGSTGKPKGVCGTEQGLLNRFLWMQELYPVVGEQRFA-FKTSVGFIDHIQEFLGAI 257

  Fly   248 MCGLAILVVPKAVTKDPQ-RLVALLERYKIRRLVLVPTLLRSLLMYLKMEGGGAAQKLLYNLQIW 311
            :...|:::.|..:.|:.. .::..||.|.|.||:.||:::|::|..|:..|..  .||...|::.
plant   258 LSSTALVIPPFTLLKENMISIIDFLEEYSISRLLAVPSMIRAILPTLQHRGHN--NKLQSCLKLV 320

  Fly   312 VCSGEPLSVSLASSFFDYFDEGVHRLYNFYGSTEVLGDVTYFACESKKQLSLYD---NVPIGIPL 373
            |.||||..|||..|......|..  ..|.||||||.||.|||.|....:|...:   :||||..:
plant   321 VLSGEPFPVSLWDSLHSLLPETC--FLNLYGSTEVSGDCTYFDCSELPRLLKTEEIGSVPIGKSI 383

  Fly   374 SNTVVYLLDADYRPVKNGEIGEIFASGLNLAAGYVNGR-DPERFLE-------NPLAVEKKYARL 430
            ||..|.||..:.:|.:    |||..|||.|:.||::.. :.|.:::       |.|..:......
plant   384 SNCKVVLLGDEDKPYE----GEICVSGLCLSQGYMHSSIESEGYVKLHNNSLCNHLTNDCGSQLY 444

  Fly   431 YRTGDYG-SLKNGSIMYEGRTDSQVKIRGHRVDLSEVEKNVAELPLVDKAIVLCYHAGQVDQAIL 494
            ||||||| .|.:|.:::.||.|..||:.|.|:.|.|:|..:...|.:.:|:||.........::.
plant   445 YRTGDYGRQLSSGDLIFIGRRDRTVKLNGKRMALEEIETTLELNPDIAEAVVLLSRDETELASLK 509

  Fly   495 AFVKLRDDAPMVTEMQMEAR--LKDKLADYMTP-QVVILEHVPLLVNGKVDRQAL--LKTYETA- 553
            |||.|..::.....:....|  :..||...|.| ..|::|.:||..:||||.:||  ||...|.
plant   510 AFVVLNKESNSSDGIIFSIRNWMGGKLPPVMIPNHFVLVEKLPLTSSGKVDYEALARLKCPTTGA 574

  Fly   554 ---NNNEGDSSIVLDFDYSQVPEDLKLTARD--LFETVGGVIGRSTRATLAPHSNFYELGGNSLN 613
               ..:.|.:|::         :::|....|  |.:.|            :...:|:.:||:||.
plant   575 QDMMQSNGTNSLL---------QNIKKAVCDALLVKEV------------SDDDDFFAIGGDSLA 618

  Fly   614 SIFTVTLLREKGYNIGIS-----EFIAAKNL--------GEIIEKMAANHDAVQ-----LEEESL 660
            :       ....:::||.     :|.:...|        |::.|.|  .|:..|     :|.::.
plant   619 A-------AHLSHSLGIDMRLIYQFRSPSRLLIYLSEKEGKLREDM--QHNTTQKLDHKIESQNG 674

  Fly   661 NACPHLKMEAVPLRLEHRQEVIDIIVASFYNKADLEQWLKPGVLRTDYSDIL------NDIWN 717
            |.   |....|||.       ..:......:|...|:...|..|:.||....      |.:|:
plant   675 NG---LVSRTVPLH-------SGVTSGPTPSKLQCEKNNSPKRLKIDYEKFSPKRMKENKLWD 727

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
e	NP_524431.2	A_NRPS	35..546	CDD:213296	155/552 (28%)
		AA-adenyl-dom	56..481	CDD:273779	133/463 (29%)
		PP-binding	580..644	CDD:278949	13/78 (17%)
AT5G35930	NP_001330867.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	163	1.000	Domainoid score	I1244
eggNOG	1	0.900	-	-		E1_COG1020
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002418
OrthoInspector	1	1.000	-	-		oto3476
orthoMCL	1	0.900	-	-		OOG6_100454
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X7632
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.710