Protein Alignment e and Aasdh

DIOPT Version :10

• Sequence 1: NP_524431.2
• Gene: e / 42521
• FlyBaseID: FBgn0000527
• Length: 879
• Species: Drosophila melanogaster
• Sequence 2: XP_061515310.1
• Gene: Aasdh / 1279502
• VectorBaseID: AGAMI1_005998
• Length: 974
• Species: Anopheles gambiae
• Alignment Length: 768
• Identity: 166/768 - (21%)
• Similarity: 294/768 - (38%)
• Gaps: 188/768 - (24%)

  Fly    54 QSSYRQMNERANRAARLLVAETHGRFLQPNSDGDFIVAVCMQPSEGLVTTLLAIWKAGGAYLPID 118
            :::|.|:.:...:.|        |...:.|.:|. ||.|.:.....|:..:..|..:|..:..||
Mosquito    29 EATYDQLWQNMLKIA--------GVLKEQNLEGK-IVGVQLFHCPALIAVIGGIIISGNTFYCID 84

  Fly   119 PSFPANRIHHILLEAKPTLVIRDDDIDAGRF-QGTPTLSTTELYAKSLQLAGSNLL--------- 173
            .|:..        :..|     |.||.|..| |.....||:.|:...: |.|..:.
Mosquito    85 KSWDE--------QLSP-----DHDICAAYFLQDFEFSSTSGLHGLQM-LVGMRIFTMPLTFSLS 135

  Fly   174 --SEEMLRGGNDHIAIVLYTSGSTGVPKGVRLPHESILNRLQWQWATFPYTANEAVSVFKTALTF 236
              |.|..|    .:|..:.||||||.||.|.:|...|:..:......|..:..:.:.|.... ||
Mosquito   136 VTSTESYR----DVAFCIRTSGSTGPPKTVLVPSTCIMPNVLSLSNRFGLSDRDVIFVCSPP-TF 195

  Fly   237 VDSIAELWGPLMCGLAILVVPKAVTKDPQRLVALL-----------------ERYKIRRLVLVP- 283
            ...:.::...|..|..:|:|..::...|:||:.:|                 .:..:..::..|
Mosquito   196 DPFVLDIVMGLRVGATLLMVDNSIRLSPKRLLDVLFPGITFMQMTPSMFTRWSKTDMLDIIFGPQ 260

  Fly   284 TLLRSLLMYLKMEGGGAAQKLLYNLQIWVCSGEPLSVSLASSFFDYFDEGVHRLYNFYGSTEVLG 348
            |.||:|::      ||....:|           |.:.....|           :||.||.|||
Mosquito   261 TTLRTLVL------GGERFPVL-----------PRAADCRVS-----------VYNIYGITEV-- 295

  Fly   349 DVTYFACESK-KQLSLYDN---VPIGIPLSNTVVYLL--------DADYRPVKNG-EIGEIFASG 400
                 :|.|. :::...||   :|:|..|..::|..:        .||:  :.|| :||:::...
Mosquito   296 -----SCWSMIQKVQSQDNQTDIPLGEVLDQSIVLQIRNEIDGSVQADH--LANGSKIGQLYIGS 353

  Fly   401 LNLAAGYVN-GRDPERFLENPLAVEKKYARLYRTGDYGSL-KNGSIMYEGRTDSQVKIRGHRVDL 463
            .:.....:. ..|.:.....|..|.:      .|||...| |.|:..|.||....:|..|.|:.|
Mosquito   354 CSRKCVILGMSEDDDTLSTMPDVVFR------ATGDLVELSKEGNYYYRGRCSRTIKRFGCRISL 412

  Fly   464 SEVEKNVAELPLVDKAIVLCYHAGQVDQAILAFVKLRDDAPMVTEMQ--MEARLKDKLADYMTPQ 526
            .|:|..:...|.|::. ..|: ..::::.::.|....||:.:...:.  |.|:|:   |:.:..:
Mosquito   413 PELEAVLQTHPSVEQC-ASCF-IEELNRLVIYFKSDTDDSSLREALWSIMRAKLR---AEMLPDE 472

  Fly   527 VVILEHVPLLVNGKVDRQALLKTYETANNNEGDSSIVLDFDYSQVPED---LKLTARDLFETVGG 588
            :..:|..||..:||:..:.|...:|....:.....|        .|.|   .:|.|.       |
Mosquito   473 LHRIEQFPLSAHGKICPKGLGVIFENLKQSRTKECI--------TPVDYFCAELNAM-------G 522

  Fly   589 VI--------GRSTRATLAPHSNFYELGGNSLNSIFTVTLLREKGYNIGISEFIA---------A 636
            ::        ||:.:  |.|:|:|.:.||.|.|:|.....| |:.:.|.:....|         .
Mosquito   523 IVHESQPIESGRTKK--LKPNSSFMDRGGTSFNAICLHATL-EEHFKIQLPGLTALLLDPLIPLE 584

  Fly   637 KNLGEIIEKMA-ANHDAVQLEEESLNACPHLKMEAVPLRLEHRQEV---IDIIVASFYNK---AD 694
            |.:..|..|:| :|.:.:|.:....|....|      |.:|.:.::   ||...:..|.:   |.
Mosquito   585 KAIDYIQSKIATSNSNCLQDDVTIQNQAEKL------LSIERQYDLKKCIDSRASIIYCQGIGAI 643

  Fly   695 LEQWLKPGVLRTDYSDILNDIWNVL---------VERDLSFVVYDTNTDRIIG 738
            |......|:|.|     :|...|.:         :|..::|..::.|...|:|
Mosquito   644 LSVGSHAGLLVT-----INIETNAIISHHLFPDRIECSVNFFTFEANVYGIVG 691

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
e	NP_524431.2	A_NRPS	34..546	CDD:341253	118/538 (22%)
		PP-binding	580..641	CDD:425746	17/77 (22%)
Aasdh	XP_061515310.1	None